Evidence map›Paper›PMID 40654727›Full record

ArticlebioRxiv : the preprint server for biology2025

No evidence of sexually antagonistic coevolution in Drosophila reproductive tract transcriptomes.

Rachel C Thayer, Elizabeth S Polston, David J Begun

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Rachel C ThayerDepartment of Evolution and Ecology, University of California, Davis, CA, USA.ORCID 0000-0001-5856-7614
Elizabeth S PolstonDepartment of Evolution and Ecology, University of California, Davis, CA, USA.
David J BegunDepartment of Evolution and Ecology, University of California, Davis, CA, USA.ORCID 0000-0002-8809-1917

Funding

Evolutionary and functional genomics of genetic novelties and expression adaptation in DrosophilaR35GM134930 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BEGUN, DAVID J · 2020 to 2024
$2.2M
Evolutionary and functional genomics of genetic novelties and expression adaptation in DrosophilaR35GM156525 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DAVID J BEGUN · 2025 to 2026
$1.0M
The function and evolution of female-expressed seminal fluid proteinsK99HD115833 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI THAYER, RACHEL C · 2024 to 2025
$249k
Gene expression and functional evolution in the Drosophila female reproductive tractF32GM146419 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI THAYER, RACHEL C · 2022 to 2024
$159k
NICHD NIH HHS K99 HD115833NIGMS NIH HHS F32 GM146419NIGMS NIH HHS R35 GM134930NIGMS NIH HHS R35 GM156525
6 · The paper itself

Abstract

Drosophila seminal fluid proteins (SFPs) are often cited as an example of interlocus sexual conflict, wherein the proteins increase male fitness while decreasing female fitness, spurring recurring female counter adaptations and rapid molecular evolution. This model predicts that male-expressed genetic variation in the accessory gland, which produces seminal fluid, should generate counter-evolving genetic pathways in females, resulting in sexual coevolution. Using a trio of

Identifiers

PMID40654727
PMCPMC12248092

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.