Evidence map›Paper›PMID 40654674›Full record

ArticlebioRxiv : the preprint server for biology2025

Biophysical and molecular mechanisms responsible for phytoplankton sinking in response to starvation.

Yanqi Wu, Vieyiti K Kouadio, Thomas R Usherwood, Justin Li, Margaret Bisher, Reshum Aurora, Aaron Z Lam, Alice R Lam, Abigail K R Lytton-Jean, Scott R Manalis and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Yanqi WuKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0002-7061-138X
Vieyiti K KouadioKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Thomas R UsherwoodKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0003-0585-2969
Justin LiKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Margaret BisherKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0002-2536-7824
Reshum AuroraKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Aaron Z LamKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Alice R LamKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0003-4332-4761
Abigail K R Lytton-JeanKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0002-1582-0066
Scott R ManalisKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0001-5223-9433
Teemu P MiettinenKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0002-5975-200X

Funding

VIRUS PRODUCTION COREP30CA014051 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Jacqueline A. Lees · 1985 to 2026
$93.9M
Measuring single-cell water content non invasively and with high precisionR01GM150901 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SCOTT R MANALIS, Teemu Petteri Miettinen · 2023 to 2026
$1.3M
NCI NIH HHS P30 CA014051NIGMS NIH HHS R01 GM150901
6 · The paper itself

Abstract

Marine phytoplankton face eco-evolutionary pressure to regulate their vertical position in the ocean to access light, which is abundant towards the surface, and nutrients, which are found deeper down the water column. All phytoplankton experience gravitational sinking, which can contribute to their vertical migration. However, the biophysical and molecular mechanisms that impact gravitational sinking have not been systematically characterized across taxa and environmental conditions. Here, we combine simulations with measurements of cell mass, volume, and composition to investigate the effects of nutrient availability on gravitational sinking in 9 representative unicellular pico- and nanoplankton species. We find that gravitational sinking becomes faster in most species when starved, but the biophysical changes responsible for this vary across species and starvation conditions. For example, the faster sinking of

Indexed as

algaecell compositioncell densitycell growthcell sizelipid contentnutrientsPhytoplanktonsinkingstarch contentStokesvertical movementwater content

Identifiers

PMID40654674
PMCPMC12248146

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.