Evidence map›Paper›PMID 40654624›Full record

ArticlebioRxiv : the preprint server for biology2025

Discovery and CryoEM Structure of FPM13, a Periplasmic Metalloprotein Unique to

Daniel L Clemens, Bai-Yu Lee, Xiaoyu Liu, Z Hong Zhou, Marcus A Horwitz

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Daniel L ClemensDepartment of Medicine, UCLA, Los Angeles, CA 90095, USA.
Bai-Yu LeeDepartment of Medicine, UCLA, Los Angeles, CA 90095, USA.
Xiaoyu LiuDepartment of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.ORCID 0000-0002-6594-9677
Z Hong ZhouDepartment of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.ORCID 0000-0002-8373-4717
Marcus A HorwitzDepartment of Medicine, UCLA, Los Angeles, CA 90095, USA.

Funding

Composition, Atomic Structure and Function of the Francisella Type 6 Secretion System, a Distinct Subtype Essential for Phagosomal Escape, Intracellular Replication, and VirulenceR01AI151055 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HORWITZ, MARCUS AARON, ZHOU, Z HONG · 2020 to 2024
$2.7M
Direct Detection Device for atomic resolution cryoEM of macromolecular complexesS10OD018111 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2014 to 2014
$598k
NIAID NIH HHS R01 AI151055NIH HHS S10 OD018111
6 · The paper itself

Abstract

We report the cryoEM structure of the

Indexed as

cryoEMFrancisellametal-binding proteinperiplasmic protein

Identifiers

PMID40654624
PMCPMC12247910

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.