ArticleFood science & nutrition2025
Anti-Inflammatory Activity and Mechanism of Stearic Acid Extract From Purslane.
Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Anti-Inflammatory Activity and Mechanism of Stearic Acid Extract From Purslane.Food science & nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purslane, as a traditional edible and medicinal herb, has been proven to have good anti-inflammatory activity. In this study, it was clarified that stearic acid was the main anti-inflammatory substance in purslane and could decrease the secretion of inflammatory cytokines, tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-10 (IL-10) in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. Meanwhile, the inhibitory effect of liposoluble extract of purslane (PLE) and stearic acid on LPS-induced ulcerative enteritis was determined. LPS-induced enteritis, including body weight loss, reduced weight of the small intestine, and histological intestinal damage, was significantly ameliorated in mice fed PLE and stearic acid. In particular, PLE could significantly reduce the levels of TNF-α, IL-6, and interleukin-1β (IL-1β) in the small intestine through NF-κB and MAPK signaling pathways. Thus, our results proved that purslane could be considered a natural anti-inflammatory medicine to combat LPS-induced inflammation and provide a theoretical basis for future applications in the field of medicine or functional food.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.