ArticleJournal of dental sciences2025
Mechanical and biological properties of cellulose nanofibers as a dental biomaterial.
Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Utilization of cellulose nanofiber in dental applications: A systematic review of in vitro evidence.The Japanese dental science review · 2025Review
- Structuring the Future of Cultured Meat: Hybrid Gel-Based Scaffolds for Edibility and Functionality.Gels (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/purpose: Plant-derived cellulose nanofibers (CNF) have emerged as a promising material for biomedical applications due to their diverse and exceptional properties but application in dental research remains limited. This study aimed to use CNF as barrier membranes or scaffold materials applied in guided bone regeneration (GBR) and guided tissue regeneration (GTR). Materials and methods: Two different thicknesses of CNF were detected by surface morphology, roughness, hydrophilicity, mechanical properties, and degradability test, and compared with GC Membrane and Ti (titanium). Additionally, the cell compatibility and cell morphology of MC3T3-E1 and HGF-1 in different groups were also studied. The alkaline phosphatase (ALP) activity of MC3T3-E1 was also examined on the 14th and 21st days. Results: Compared to the GC membrane, CNF showed better mechanical properties but remained inferior to titanium. Soaking increased their roughness and hydrophilicity while reducing mechanical strength. CNF also exhibited degradability, and good biocompatibility, with ALP expression significantly elevated at 14 and 21 days. Conclusion: The results of this study on various properties of CNF indicate that CNF has the potential to become a novel dental biomaterial.
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Registered trials
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