ArticleJournal of mood and anxiety disorders2023
Prognostic and prescriptive predictors of PTSD response to prolonged exposure and sertraline.
Article in Journal of mood and anxiety disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00127673 (Effectiveness of PTSD Treatment), which is not on this map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of PTSD Treatment: CBT Versus Sertraline
Who cites it
2 citing papers in PubMed.
- Who engages? Machine learning insights into digital mindfulness-based intervention for generalized anxiety disorder.Journal of affective disorders · 2026Trial
- Novel psychedelic interventions for post-traumatic stress disorder and their promise for precision medicine.Therapeutic advances in psychopharmacology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In developing personalized care for PTSD, baseline predictors that inform clinicians' and patients' decision making across treatment options are limited. In 200 individuals with PTSD in a multi-site, doubly randomized preference trial, baseline psychopathology, personality/mood regulation, health/social functioning, treatment credibility and history, and demographic factors predicted PTSD severity from baseline, ten sessions, to post-treatment. Using a stepwise prognostic and prescriptive modeling approach, rates of change and post-treatment outcomes between prolonged exposure [PE] vs sertraline and preferred vs non-preferred treatments were examined. Stronger credibility of PE predicted faster improvement ( Data Availability: All data, program code, and other methods developed by others have been cited appropriately in text. The dataset for this study comes from a previously published clinical trial [NCT00127673, 29] and is available by request by competent researchers. Computer syntax used for this study is available upon request. Research materials, including treatment rationales and manuals, are available upon request.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.