Evidence map›Paper›PMID 40654364›Full record

ArticleActa pharmaceutica Sinica. B2025

ALKBH3-regulated m

Yuhua Deng, Zhiyan Chen, Peixian Chen, Yaming Xiong, Chuling Zhang, Qiuyuan Wu, Huiqi Huang, Shuqing Yang, Kun Zhang, Tiancheng He and 5 more

Abstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yuhua DengDepartment of Breast Surgery, the First People's Hospital of Foshan, Foshan 528100, China.
Zhiyan ChenDepartment of Breast Surgery, the First People's Hospital of Foshan, Foshan 528100, China.
Peixian ChenDepartment of Breast Surgery, the First People's Hospital of Foshan, Foshan 528100, China.
Yaming XiongInstitute of Translational Medicine Research, the First People's Hospital of Foshan, Foshan 528100, China.
Chuling ZhangInstitute of Translational Medicine Research, the First People's Hospital of Foshan, Foshan 528100, China.
Qiuyuan WuDepartment of Breast Surgery, the First People's Hospital of Foshan, Foshan 528100, China.
Huiqi HuangDepartment of Breast Surgery, the First People's Hospital of Foshan, Foshan 528100, China.
Shuqing YangDepartment of Breast Surgery, the First People's Hospital of Foshan, Foshan 528100, China.
Kun ZhangDepartment of Breast Surgery, the First People's Hospital of Foshan, Foshan 528100, China.
Tiancheng HeDepartment of Breast Surgery, the First People's Hospital of Foshan, Foshan 528100, China.
Wei LiDepartment of Breast Surgery, the First People's Hospital of Foshan, Foshan 528100, China.
Guolin YeDepartment of Breast Surgery, the First People's Hospital of Foshan, Foshan 528100, China.
Wei LuoInstitute of Translational Medicine Research, the First People's Hospital of Foshan, Foshan 528100, China.
Hongsheng WangGuangdong Provincial Key Laboratory of Chiral Molecule and Drug Discovery, State Key Laboratory of Anti-Infective Drug Discovery and Development, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Dan ZhouDepartment of Breast Surgery, the First People's Hospital of Foshan, Foshan 528100, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemotherapy is currently the mainstay of systemic management for triple-negative breast cancer (TNBC), but chemoresistance significantly impacts patient outcomes. Our research indicates that Doxorubicin (Dox)-resistant TNBC cells exhibit increased glycolysis and ATP generation compared to their parental cells, with this metabolic shift contributing to chemoresistance. We discovered that ALKBH3, an m

Indexed as

3′UTRALDOAALKBH3ChemoresistanceGlycolysism1AStabilityTNBC

Identifiers

PMID40654364
PMCPMC12254773

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.