Evidence map›Paper›PMID 40654348›Full record

ArticleActa pharmaceutica Sinica. B2025

Submicron-sized superantigen biomimetic liposomes with highly efficient pulmonary accumulation to remodel local immune microenvironment for cancer chemoimmunotherapy.

Bochuan Yuan, Feng Zhang, Qiucheng Yan, Wanmei Wang, Zhangyu Li, Lina Du, Yiguang Jin, Fei Xie

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bochuan YuanCollege of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing 100048, China.
Feng ZhangBeijing Institute of Radiation Medicine, Beijing 100850, China.
Qiucheng YanBeijing Institute of Radiation Medicine, Beijing 100850, China.
Wanmei WangBeijing Institute of Radiation Medicine, Beijing 100850, China.
Zhangyu LiBeijing Institute of Radiation Medicine, Beijing 100850, China.
Lina DuBeijing Institute of Radiation Medicine, Beijing 100850, China.
Yiguang JinBeijing Institute of Radiation Medicine, Beijing 100850, China.
Fei XieCollege of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing 100048, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastatic lung cancer continues to cause a high number of deaths due to high malignancy and poor prognosis, and the efficacy of typical chemotherapy or immunotherapy is less than ideal due to the low pulmonary accumulation and targeting of therapeutics. Here, a submicron-sized biomimetic liposome was formulated for the lung-targeted co-delivery of bacterial superantigen and paclitaxel. Recombinant staphylococcal enterotoxin C2 (rSEC2), a bacterial superantigen, was expressed with the

Indexed as

Bacterial superantigenBiomimetic liposomeChemoimmunotherapyImmune microenvironmentImmunosuppression reversalLung targetingMetastatic lung cancerSubmicron liposome

Identifiers

PMID40654348
PMCPMC12254850

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.