Evidence map›Paper›PMID 40654316›Full record

ArticleThe European journal of neuroscience2025

GABA

Jennifer Bostel, Alina J Kürten, Antonia Beiersdorfer

Abstract read
In one paragraph

Article in The European journal of neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. GABAThe European journal of neuroscience · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jennifer BostelDivision of Neurophysiology, University of Hamburg, Hamburg, Germany.ORCID 0009-0007-9131-9648
Alina J KürtenDivision of Neurophysiology, University of Hamburg, Hamburg, Germany.
Antonia BeiersdorferDivision of Neurophysiology, University of Hamburg, Hamburg, Germany.ORCID 0000-0003-0976-005X

Funding

Department of Biology, University of Hamburg
6 · The paper itself

Abstract

The prefrontal cortex (PFC) is a cortical brain region whose multifaceted functions are based on a complex interplay between excitatory pyramidal neurons, inhibitory GABAergic interneurons, and astrocytes maintaining a fine-tuned excitation/inhibition balance (E/I balance). The regulation of the E/I balance in cortical networks is crucial as the disruption leads to impairments in PFC-associated behavior and pathologies. Astrocytes express specific GABA receptors that mediate intracellular Ca

Indexed as

AstrocytesCalciumCalcium SignalingPrefrontal CortexReceptors, GABA-BAnimalsgamma-Aminobutyric AcidMaleMiceMice, Inbred C57BLCalciumgamma-Aminobutyric AcidReceptors, GABA-Bastrocytescalcium signalingGABAB receptorintracellular calcium storesPLC/IP3‐signaling cascadeprefrontal cortex

Identifiers

PMID40654316
PMCPMC12257579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.