Evidence map›Paper›PMID 40654257›Full record

ArticleAllergy2025

Aging Increases the Severity of Anaphylaxis Through Changes in Mast Cell Numbers and Histamine Sensitivity.

Jasper B J Kamphuis, Alexia Loste, William P M Worrall, Nadine Serhan, Thomas Villeneuve, Pol André Apoil, Benjamin Trouche-Estival, IHU HealthAge INSPIRE/Open Science group, Laurent Guilleminault, Nicolas Gaudenzio and 1 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jasper B J KamphuisToulouse Institute for Infectious and Inflammatory Diseases (INFINITy), INSERM UMR1291, CNRS UMR5051, University of Toulouse, Toulouse, France.ORCID https://orcid.org/0000-0002-8494-613X
Alexia LosteToulouse Institute for Infectious and Inflammatory Diseases (INFINITy), INSERM UMR1291, CNRS UMR5051, University of Toulouse, Toulouse, France.
William P M WorrallToulouse Institute for Infectious and Inflammatory Diseases (INFINITy), INSERM UMR1291, CNRS UMR5051, University of Toulouse, Toulouse, France.ORCID https://orcid.org/0000-0003-2507-8173
Nadine SerhanToulouse Institute for Infectious and Inflammatory Diseases (INFINITy), INSERM UMR1291, CNRS UMR5051, University of Toulouse, Toulouse, France.
Thomas VilleneuveToulouse Institute for Infectious and Inflammatory Diseases (INFINITy), INSERM UMR1291, CNRS UMR5051, University of Toulouse, Toulouse, France.ORCID https://orcid.org/0000-0002-1947-3401
Pol André ApoilToulouse Institute for Infectious and Inflammatory Diseases (INFINITy), INSERM UMR1291, CNRS UMR5051, University of Toulouse, Toulouse, France.ORCID https://orcid.org/0000-0002-1057-4919
Benjamin Trouche-EstivalInstitut Fédératif de Biologie, University Hospital Centre of Toulouse, Toulouse, France.
IHU HealthAge INSPIRE/Open Science group
Laurent GuilleminaultToulouse Institute for Infectious and Inflammatory Diseases (INFINITy), INSERM UMR1291, CNRS UMR5051, University of Toulouse, Toulouse, France.
Nicolas GaudenzioToulouse Institute for Infectious and Inflammatory Diseases (INFINITy), INSERM UMR1291, CNRS UMR5051, University of Toulouse, Toulouse, France.ORCID https://orcid.org/0000-0002-5648-509X
Laurent L ReberToulouse Institute for Infectious and Inflammatory Diseases (INFINITy), INSERM UMR1291, CNRS UMR5051, University of Toulouse, Toulouse, France.ORCID https://orcid.org/0000-0003-3384-6769

Funding

Agence Nationale de la Recherche ANR-23-IAHU-0011European Regional Development Fund MP0022856European Research Council ERC-2021-CoG 101043749European Research Council ERC-2023-COG 101124255Fondation pour la Recherche Médicale EQU202103012566Fondation pour la Recherche Médicale SPF202005011962Institut National de la Santé et de la Recherche MédicaleRegion Occitanie/Pyrénées-Méditerranée 1901175
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anaphylaxisanimal modelshistamineIgEmast cells

Identifiers

PMID40654257
PMCPMC12486355

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.