Evidence map›Paper›PMID 40654240›Full record

ArticleJournal of the American Heart Association2025

Low Burden of Arrhythmia in Pediatric Patients and Patients With Congenital Heart Disease Participating in Cardiac Rehabilitation.

Paul W Warren, Clifford Chin, Alexander R Opotowsky, Shankar Baskar, Richard J Czosek, Wayne A Mays, Zhiqian Gao, Adam W Powell

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paul W WarrenThe Heart Institute, Cincinnati Children's Hospital Medical Center Cincinnati OH USA.ORCID 0000-0002-3432-1430
Clifford ChinThe Heart Institute, Cincinnati Children's Hospital Medical Center Cincinnati OH USA.ORCID 0000-0001-5168-456X
Alexander R OpotowskyThe Heart Institute, Cincinnati Children's Hospital Medical Center Cincinnati OH USA.ORCID 0000-0002-6107-2281
Shankar BaskarThe Heart Institute, Cincinnati Children's Hospital Medical Center Cincinnati OH USA.
Richard J CzosekThe Heart Institute, Cincinnati Children's Hospital Medical Center Cincinnati OH USA.ORCID 0000-0001-7497-9555
Wayne A MaysThe Heart Institute, Cincinnati Children's Hospital Medical Center Cincinnati OH USA.
Zhiqian GaoThe Heart Institute, Cincinnati Children's Hospital Medical Center Cincinnati OH USA.ORCID 0000-0002-5963-2657
Adam W PowellThe Heart Institute, Cincinnati Children's Hospital Medical Center Cincinnati OH USA.ORCID 0000-0002-5537-032X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac rehabilitation (CR) is underused in pediatric and congenital heart disease populations. Concern about arrhythmia risk may be an obstacle to CR referral. We sought to describe the frequency and risk factors for arrhythmia in patients who participated in a standardized CR program.

methodsWe conducted a retrospective chart review of all patients who completed at least 1 CR encounter from 2017 to 2022 at a pediatric cardiology center. We used descriptive statistics to determine the frequency of atrial and ventricular ectopy. Logistic regression was performed to identify predictors of frequent ventricular ectopy, nonsustained ventricular tachycardia, or ventricular tachycardia.

resultsThere were 177 patients who participated in 4494 rehabilitation encounters over the 6-year study period (median age, 17 years [14-22]). Most patients had congenital heart disease (63%). Moderate or severe systolic dysfunction was noted in 14% of patients. Presence of an implantable cardioverter-defibrillator (9% of patients) and a ventricular assist device (5% of patients) was noted. Nonsustained ventricular tachycardia occurred in 7 patients (3.9%) across 18 sessions (0.4%). There was an episode of sustained ventricular tachycardia resulting in an appropriate implantable cardioverter-defibrillator shock. There were no deaths. Patients ≥18 years old (odds ratio, 2.7 [95% CI, 1.1 - 6.4]) were more likely to have frequent ventricular ectopy, nonsustained ventricular tachycardia, or ventricular tachycardia.

conclusionsSupervised CR in pediatric and congenital heart disease populations is associated with a low risk for clinically significant arrhythmias, and should not be an obstacle to referral for individuals who would otherwise benefit from CR.

Indexed as

Arrhythmias, CardiacCardiac RehabilitationHeart Defects, CongenitalAdolescentDefibrillators, ImplantableFemaleHumansMaleRetrospective StudiesRisk AssessmentRisk FactorsYoung Adultarrhythmiacardiac rehabilitationcongenital heart diseaseexercise safetypediatricventricular ectopy

Identifiers

PMID40654240
PMCPMC12533627

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.