Evidence map›Paper›PMID 40654087›Full record

ArticleChembiochem : a European journal of chemical biology2025

A Browser-Based Tool for Assessing Accuracy of Isothermal Titration Calorimetry-Derived Parameters: K

Tong Ye Wang, Amit Bijlani, Emily Hoi Pui Chao, Philip E Johnson, Sergey N Krylov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tong Ye WangDepartment of Chemistry, York University, Toronto, Ontario, M3J 1P3, Canada.ORCID https://orcid.org/0000-0001-9462-7194
Amit BijlaniDepartment of Chemistry, York University, Toronto, Ontario, M3J 1P3, Canada.ORCID https://orcid.org/0009-0006-8272-7183
Emily Hoi Pui ChaoDepartment of Chemistry, York University, Toronto, Ontario, M3J 1P3, Canada.ORCID https://orcid.org/0009-0002-6434-0891
Philip E JohnsonDepartment of Chemistry, York University, Toronto, Ontario, M3J 1P3, Canada.ORCID https://orcid.org/0000-0002-5573-4891
Sergey N KrylovDepartment of Chemistry, York University, Toronto, Ontario, M3J 1P3, Canada.ORCID https://orcid.org/0000-0003-3270-2130

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2018-0631Natural Sciences and Engineering Research Council of Canada RGPIN-2022-04563York University grant to the Catalyzing Interdisciplinary Research Cluster "Technologies for Identification and Control of Infectious Diseases"
6 · The paper itself

Abstract

Accurate determination of equilibrium dissociation constants (K

Indexed as

CalorimetrySoftwareThermodynamicsaccuracy confidence intervalbinding affinityequilibrium dissociation constanterror analysisisothermaltitration calorimetrymonte carlo simulationprotein–ligand interactions

Identifiers

PMID40654087
PMCPMC12376257

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.