Evidence map›Paper›PMID 40653995›Full record

ArticleBJOG : an international journal of obstetrics and gynaecology2025

Association Between Post-Partum Anaemia and Depressive Symptoms at Two Months After Vaginal Delivery: A Secondary Analysis of the TRAAP Trial.

Lola Loussert, Loïc Sentilhes, Alizée Froeliger, Aurélien Seco, Marie Pierre Bonnet, Sarah Tebeka, Catherine Deneux-Tharaux, TRAAP study group

Abstract readMulticenter Study
In one paragraph

Article in BJOG : an international journal of obstetrics and gynaecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Disrespectful Maternity Care and Postpartum Depression at 2 Months: A Population-Based Study.BJOG : an international journal of obstetrics and gynaecology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lola LoussertUniversité Paris Cité Institut Santé Des Femmes, Centre for Research in Epidemiology and Statistics (CRESS) U1153, Obstetrical Perinatal and Pediatric Epidemiology Research Team (Epopé), INSERM, INRAE, Paris, France.ORCID https://orcid.org/0009-0004-0539-3752
Loïc SentilhesDepartment of Obstetrics and Gynecology, Bordeaux University Hospital, Bordeaux, France.
Alizée FroeligerUniversité Paris Cité Institut Santé Des Femmes, Centre for Research in Epidemiology and Statistics (CRESS) U1153, Obstetrical Perinatal and Pediatric Epidemiology Research Team (Epopé), INSERM, INRAE, Paris, France.
Aurélien SecoClinical Research Unit Necker Cochin, APHP, Paris, France.
Marie Pierre BonnetUniversité Paris Cité Institut Santé Des Femmes, Centre for Research in Epidemiology and Statistics (CRESS) U1153, Obstetrical Perinatal and Pediatric Epidemiology Research Team (Epopé), INSERM, INRAE, Paris, France.
Sarah TebekaDepartment of Psychiatry, Louis Mourier Hospital, Colombes, France.ORCID https://orcid.org/0000-0003-0269-4600
Catherine Deneux-TharauxUniversité Paris Cité Institut Santé Des Femmes, Centre for Research in Epidemiology and Statistics (CRESS) U1153, Obstetrical Perinatal and Pediatric Epidemiology Research Team (Epopé), INSERM, INRAE, Paris, France.ORCID https://orcid.org/0000-0002-6561-3321
TRAAP study group

Funding

Ministère de la Santé
6 · The paper itself

Abstract

objectiveTo assess the association between maternal haemoglobinaemia in the immediate post-partum period and PPD symptoms 2 months after vaginal delivery.

designAncillary cohort study of the TRAAP trial, a multicentre trial.

settingIn France, 2015-2016. POPULATION: Women with a singleton pregnancy and vaginal delivery ≥ 35 weeks. We excluded women with known psychiatric conditions and those who were non-respondent to the Edinburgh Post-partum Depression Scale (EPDS) questionnaire.

methodsThe exposure was immediate post-partum haemoglobinemia (systematically collected in TRAAP trial) as a continuous variable. MAIN OUTCOME: PPD symptoms at 2 months post-partum, defined as an EPDS score ≥ 11. We also differentiated two levels of PPD symptom severity: moderate (11 ≤ EPDS < 13) and severe (EPDS ≥ 13) depressive symptoms.

resultsAmongst the 2672 women included, 1115 (43.6%) had post-partum anaemia (haemoglobin < 11 g/dL) in the immediate post-partum and 369 (13.8%) had PPD symptoms at 2 months. The relation between haemoglobin and PPD symptoms was linear. In the multivariable analysis, each 1 g/dL increase in haemoglobin level was associated with a 9% decrease in the risk of post-partum depression symptoms (adjusted Relative Risk 0.91; 95% CI 0.82-0.997). Post-partum haemoglobin was specifically associated with moderate depressive symptoms (adjusted Relative Risk 0.84; 95% CI, 0.72-0.98) but not with severe depressive symptoms (aRR 0.95; 95% CI, 0.84-1.07).

conclusionsIn women with vaginal delivery, each 1 g/dL increase in haemoglobin level was associated with a 9% decrease in the risk of post-partum depression symptoms.

Indexed as

AnemiaDelivery, ObstetricDepression, PostpartumPostpartum PeriodAdultCohort StudiesFemaleFranceHemoglobinsHumansPregnancyHemoglobinsmaternal mental healthpost‐partum anaemiapost‐partum depressionpost‐partum haemoglobin levelvaginal delivery

Identifiers

PMID40653995
PMCPMC12411663

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.