Evidence map›Paper›PMID 40653817›Full record

ArticleActa orthopaedica2025

Association between body mass index and return to work following primary knee arthroplasty: a population-based cohort study on 6,128 patients from Danish national registers.

Julie B Pajaniaye, Peter Alsing, Martin G Stisen, Erzsébet Horváth-Puhó, Maaike G J Gademan, Alma B Pedersen, Inger Mechlenburg

Abstract read
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Article in Acta orthopaedica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Julie B PajaniayeDepartment of Clinical Epidemiology, Aarhus University Hospital; Department of Orthopaedic Surgery, Aarhus University Hospital; Department of Dentistry and Oral Health, Aarhus University, Denmark jp@dent.au.dk.ORCID 0000-0003-3976-1627
Peter AlsingDepartment of Clinical Epidemiology, Aarhus University Hospital; Department of Orthopaedic Surgery, Aarhus University Hospital, Denmark.
Martin G StisenDepartment of Orthopaedic Surgery, Aarhus University Hospital; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-8743-8616
Erzsébet Horváth-PuhóDepartment of Clinical Epidemiology, Aarhus University Hospital; Center for Population Medicine, Aarhus University and Aarhus University Hospital, Denmark.
Maaike G J GademanCenter for Population Medicine, Aarhus University and Aarhus University Hospital, Denmark; Department of Orthopaedics, Leiden University Medical Centre, University of Leiden, Leiden, the Netherlands.ORCID 0000-0002-6106-3385
Alma B PedersenDepartment of Clinical Epidemiology, Aarhus University Hospital; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-3288-9401
Inger MechlenburgDepartment of Orthopaedic Surgery, Aarhus University Hospital; Department of Clinical Medicine, Aarhus University, Aarhus; Research Center for Activity and Prevention, VIA University College, Aarhus, Denmark.ORCID 0000-0001-5432-8691

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeWith more knee arthroplasties (KAs) performed in working-age patients, interest in return to work (RTW) increases. We aimed to investigate the association between body mass index (BMI) and RTW after primary KA and whether the association varies by sex, age, comorbidity, and socioeconomic position.

methodsFrom Danish national registries, we included 6,128 patients aged 18 to 60 years undergoing KA from 2008-2018. Exposure was BMI in categories < 25.0, 25.0-29.9, 30.0-34.9, 35.0-39.9, and ≥ 40.0. Outcome was RTW after KA. We estimated cumulative incidence proportions (CIP) of RTW. Cox regression was used to calculate hazard ratios (HRs) with 95% confidence intervals (CI).

resultsMedian time to RTW was 70 days. Overall CIP for RTW was 63% (CI 62-65) at 3 months. With BMI < 25 as reference, CIP was 65% (n = 1,401) for BMI 25.0-29.9, 64% (n = 1,130) for BMI 30.0-34.9, 60% (n = 528) for BMI 35.0-39.9, and 60% (n = 260) for BMI ≥ 40.0, corresponding to an adjusted HR of 1.06 (CI 0.98-1.15), 1.02 (CI 0.94-1.11), 0.97 (CI 0.88-1.06), and 0.96 (CI 0.85-1.08). Men with BMI 35.0-39.9 and ≥ 40 had an adjusted HR of 0.89 (CI 0.76-1.05) and 0.87 (CI 0.70-1.10). None of the associations were statistically significant. Age, comorbidity, and socioeconomic position did not modify the association between BMI and RTW.

conclusionMore than 60% of patients RTW within 3 months but we found no association between BMI and RTW after primary KA.

Indexed as

Arthroplasty, Replacement, KneeBody Mass IndexReturn to WorkAdolescentAdultCohort StudiesDenmarkFemaleHumansMaleMiddle AgedRegistriesYoung Adult

Identifiers

PMID40653817
PMCPMC12257360

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.