Evidence map›Paper›PMID 40653812›Full record

ArticleJournal of applied clinical medical physics2025

ADAPT-marketplace - A web-application for XML-based template sharing in radiation oncology.

Dennis N Stanley, Joseph Harms, Gaurav N Rathi, Joel A Pogue, Ritish Nedunoori, John B Fiveash, Richard A Popple, Carlos E Cardenas

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dennis N StanleyDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0003-4792-748X
Joseph HarmsDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0003-2441-9853
Gaurav N RathiDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Joel A PogueDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0003-4450-6698
Ritish NedunooriDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
John B FiveashDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0002-1129-2884
Richard A PoppleDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0003-1252-738X
Carlos E CardenasDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Funding

National Institutes of Health/National Cancer Institute award L30CA284339National Institutions of Health/National Cancer Institute LRP0000018407NCATS NIH HHS 5KL2TR003097-05University of Alabama at Birmingham UABRO2022
6 · The paper itself

Abstract

purposeThe adaption of radiotherapy (RT) plans in response to anatomical and physiological changes during treatment marks a significant shift toward personalized cancer care. However, the complexity of Online Adaptive Radiotherapy (OART) procedures often leads to variability in treatment quality across institutions. The development of planning templates, particularly through the Ethos treatment planning system (TPS) and Intelligent Optimization Engine (IOE) (Varian Medical Systems, Palo Alto, CA), plays a crucial role in standardizing and streamlining OART. To address the challenges of sharing and optimizing treatment templates across diverse clinical environments, we developed the ADaptive rAdiotherapy Planning Template (ADAPT-) Marketplace to facilitate the exchange of XML-based templates and promote collaborative innovation in the OART community.

methodsADAPT-Marketplace was developed using the Django web framework, chosen for its security, scalability, and versatility. The platform supports the sharing of XML-based treatment planning templates, compatible with Ethos TPS, and includes features for uploading, downloading, comparing, and editing templates. The development followed a structured process, involving collaborator consultations, prototyping, and both alpha and beta testing. Testing phases included predefined tasks and unscripted evaluations, with feedback collected to refine the platform prior to its official launch.

resultsSince its launch in July 2023, ADAPT-Marketplace has registered 65 users from 16 countries and 38 institutions, including academic, non-academic and industrial sectors. Over 50 templates have been uploaded, covering treatment sites such as the pelvis, thorax, head-and-neck, and abdomen. Feedback from alpha and beta testing resulted in key improvements, including enhanced navigation, template validation, and user experience.

conclusionADAPT-marketplace provides a centralized platform for sharing and collaborating on treatment planning templates, offering the potential to improve research productivity, facilitate knowledge exchange, and standardize OART practices across institutions.

Indexed as

InternetNeoplasmsProgramming LanguagesRadiation OncologyRadiotherapy Planning, Computer-AssistedSoftwareHumansRadiotherapy DosageRadiotherapy, Intensity-Modulatedethosonline adaptive radiotherapyplanning templatesradiation oncologytemplate repositorytreatment planningXML

Identifiers

PMID40653812
PMCPMC12256657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.