Evidence map›Paper›PMID 40653803›Full record

ArticleThe International journal of eating disorders2025

Psychobiological Exercise Response: A Pilot Investigation of a Laboratory Exercise Assessment Paradigm Among Young Women With Eating Disorders.

Katherine Schaumberg, Mahathi Gavuji, Agatha A Laboe, Lauren E Pictor, Kevin M Crombie, Sasha Gorrell

Abstract read
In one paragraph

Article in The International journal of eating disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katherine SchaumbergDepartment of Psychology, University of Texas at Austin, Austin, Texas, USA.ORCID 0000-0003-3193-2233
Mahathi GavujiDepartment of Psychiatry, University of Wisconsin - Madison, Madison, Wisconsin, USA.
Agatha A LaboeDepartment of Psychiatry, University of Wisconsin - Madison, Madison, Wisconsin, USA.ORCID 0000-0002-5089-4087
Lauren E PictorDepartment of Psychological Sciences, Auburn University, Auburn, Alabama, USA.
Kevin M CrombieDepartment of Kinesiology, The University of Alabama, Tuscaloosa, Alabama, USA.
Sasha GorrellDepartment of Psychiatry and Behavioral Sciences, University of California - San Francisco, San Francisco, California, USA.ORCID 0000-0002-8861-8547

Funding

UCSD Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) Faculty Development ProgramR25NS117367 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Victoria B Risbrough, Joann Trejo · 2020 to 2026
$1.6M
Neural Correlates of Reinforcement Learning Specific to Hyperactivityin Adolescent Anorexia NervosaK23MH126201 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GORRELL, SASHA CATHERINE · 2021 to 2025
$848k
Driven exercise and risk for eating disorders: A combined genetic and longitudinal epidemiological investigationK01MH123914 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI SCHAUMBERG, KATHERINE · 2020 to 2023
$743k
The influence of aerobic exercise on consolidation of fear extinction learning in PTSDK01MH132545 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI Kevin M Crombie · 2023 to 2026
$721k
Characterizing Acute Exercise Response in Restrictive Eating DisordersR21MH131787 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI GORRELL, SASHA CATHERINE, SCHAUMBERG, KATHERINE · 2023 to 2023
$450k
Brain and Behavior Research FoundationNIMH NIH HHS K01 MH123914NIMH NIH HHS K01MH123914NIMH NIH HHS K01 MH132545NIMH NIH HHS K01MH132545NIMH NIH HHS K23 MH126201NIMH NIH HHS K23MH126201NIMH NIH HHS R21 MH131787NIMH NIH HHS R21MH131787NINDS NIH HHS R25 NS117367
6 · The paper itself

Abstract

objectiveCompulsive exercise is a common feature of eating disorders (EDs) but understanding of factors that drive this symptom remains limited. This pilot trial evaluated psychobiological response to in-laboratory exercise among females (14-22 years) with and without restrictive eating pathology. We aimed to demonstrate the feasibility of two exercise assessment protocols and provide initial estimates of acute exercise effects on affect, body image, and circulating blood-based biomarkers (brain-derived neurotrophic factor [BDNF], cortisol, N-arachodonoylethanolamine [AEA], 2-arachidonoylglycerol [2-AG], leptin).

methodTwenty females with restrictive EDs and 20 healthy controls completed three study visits, including two bouts of stationary cycling (30-min prescribed pace vs. ≤ 30-min self-paced) and two complementary periods of rest. During visits, participants also consumed a milkshake, self-reported state affect and body image, and participated in pre- and post-exercise blood draws.

resultsPer established thresholds, both tasks were determined feasible and safe, with initial evidence of validity in eliciting affective and body image change. In both exercise conditions, the ED group experienced more positive (Cohen's d = 0.10-0.61) and less negative affect (Cohen's d = -0.72 - -0.22) compared to controls, along with greater positive body image shifts (Cohen's d = 0.20-0.66). Body image shifts in the ED group correlated with higher drive for muscularity and lower BMI. DISCUSSION: Findings suggest perceived effects of exercise on body weight/shape may reinforce exercise maintenance in the context of EDs.

Indexed as

AffectBody ImageExerciseFeeding and Eating DisordersAdolescentAdultBiomarkersBrain-Derived Neurotrophic FactorFeasibility StudiesFemaleHumansHydrocortisoneLeptinPilot ProjectsYoung AdultBiomarkersBrain-Derived Neurotrophic FactorHydrocortisoneLeptinaffectbiomarkersbody imagecompulsive exerciseeating disordersexercise

Identifiers

PMID40653803
PMCPMC12501568

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.