Evidence map›Paper›PMID 40653789›Full record

ArticleJournal of applied clinical medical physics2025

Novel validation of HDR brachy therapy dosimetry for cervical cancer using egs_brachy Monte Carlo simulations: a comparative analysis with Oncentra treatment planning system.

Duong Thanh Tai, Nguyen Thi Anh Thu, Tran Thien Thanh, Pham Anh Tuan, Marc J P Chamberland, Peter Sandwall, David Bradley, James C L Chow

Abstract readComparative StudyValidation Study
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Duong Thanh TaiDepartment of Medical Physics, Faculty of Medicine, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0000-0001-7276-8105
Nguyen Thi Anh ThuDepartment of Nuclear Physics, Faculty of Physics and Engineering Physics, University of Science, Ho Chi Minh City, Vietnam.
Tran Thien ThanhDepartment of Nuclear Physics, Faculty of Physics and Engineering Physics, University of Science, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0000-0002-9866-4926
Pham Anh TuanNuclear Medicine and Oncology Centre, Bach Mai Hospital, Ha Noi, Vietnam.
Marc J P ChamberlandDepartment of Radiation Oncology, University of Vermont Medical Center, Vermont, USA.
Peter SandwallDepartment of Radiation Oncology OhioHealth Mansfield, Ohio, USA.ORCID https://orcid.org/0000-0001-9962-7281
David BradleyApplied Physics and Radiation Technologies group, CCDCU, School of Engineering and Technology, Sunway University, Sunway City, Malaysia.ORCID https://orcid.org/0000-0001-9485-5242
James C L ChowDepartment of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-4202-4855

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to validate HDR brachytherapy dosimetry for cervical cancer patients utilizing the egs_brachy Monte Carlo (MC) simulation.

methodsThree cervical cancer patients treated with

resultsTPS-calculated doses were greater than those obtained from MC simulations. For the CTV, the median percentage differences were 7.9% (Q1: 6.4%, Q3: 9.8%; range: 0.4%-10.4%) for D

conclusionCTV and critical organ doses calculated by the TPS were consistently greater than those obtained from MC simulations. This suggests that the TPS may overestimate dose distributions, especially in heterogeneous regions like the pelvis. These results emphasize the need for continued validation of TPS algorithms in HDR brachytherapy for cervical cancer.

Indexed as

BrachytherapyIridium RadioisotopesMonte Carlo MethodOrgans at RiskRadiotherapy Planning, Computer-AssistedUterine Cervical NeoplasmsFemaleHumansRadiometryRadiotherapy DosageRadiotherapy, Intensity-ModulatedIridium-192Iridium Radioisotopesbrachytherapydose calculationsegs_brachyheterogeneityMonte Carlo simulationradiation treatment planningTG‐186TG‐43

Identifiers

PMID40653789
PMCPMC12256655

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.