Evidence map›Paper›PMID 40653716›Full record

ArticleACS synthetic biology2025

Genetically Encoded

Theodor Simak, Florian Stracke, Oskar Smrzka, Gordana Wozniak-Knopp

Abstract read
In one paragraph

Article in ACS synthetic biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Theodor SimakChristian Doppler Laboratory for Innovative Immunotherapeutics, BOKU University, Muthgasse 18, 1190 Vienna, Austria.
Florian StrackeChristian Doppler Laboratory for Innovative Immunotherapeutics, BOKU University, Muthgasse 18, 1190 Vienna, Austria.
Oskar SmrzkaAblevia biotech GmbH, Maria Jacobi Gasse 1, 1030 Vienna, Austria.
Gordana Wozniak-KnoppChristian Doppler Laboratory for Innovative Immunotherapeutics, BOKU University, Muthgasse 18, 1190 Vienna, Austria.ORCID 0000-0002-4069-070X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptide libraries present have improved means to effectively identify epitopes of antibodies, either as monoclonal reagents or polyclonal constituents of the immune response, which includes characterization of vaccination responses, profiling of allergic reactions, and screening of patient samples for autoantibodies. In all of these examples, there is an urgent demand for simple and inexpensive target epitope screening. Here, we present a method for epitope identification, based on the yeast display of overlapping peptides conformationally constrained within the

Indexed as

Capsid ProteinsPeptide LibraryPeptides, CyclicAntibodies, MonoclonalEpitopesHumansRituximabSaccharomyces cerevisiaeAntibodies, MonoclonalCapsid ProteinsEpitopesPeptide LibraryPeptides, CyclicRituximabantibody−antigen interactionautoantibodiescyclic peptidesepitope mappingneurological diseaseyeast display

Identifiers

PMID40653716
PMCPMC12362601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.