Evidence map›Paper›PMID 40653712›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2026

Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus.

Mona Prasad, Grecio J Sandoval, George R Saade, Brenna L Hughes, Rebecca G Clifton, Uma M Reddy, Anna Bartholomew, Ashley Salazar, Edward K Chien, Alan T N Tita and 13 more

Abstract readEvaluation Study
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Mona PrasadDepartment of Obstetrics and Gynecology of the Ohio State University, Columbus, Ohio, USA.ORCID 0000-0003-4157-656X
Grecio J SandovalGeorge Washington University Biostatistics Center, Washington, DC, USA.ORCID 0000-0002-3601-6712
George R SaadeDepartment of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0001-7925-5302
Brenna L HughesBrown University, Women and Infants Hospital of Rhode Island, Providence, Rhode Island, USA.
Rebecca G CliftonGeorge Washington University Biostatistics Center, Washington, DC, USA.
Uma M ReddyEunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA.
Anna BartholomewDepartment of Obstetrics and Gynecology of the Ohio State University, Columbus, Ohio, USA.
Ashley SalazarDepartment of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas, USA.
Edward K ChienDepartment of Obstetrics and Gynecology, Case Western Reserve University, Cleveland, Ohio, USA.
Alan T N TitaDepartment of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
John M ThorpDepartment of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Torri D MetzDepartment of Obstetrics and Gynecology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
Ronald J WapnerDepartment of Obstetrics and Gyneology, Columbia University, New York, New York, USA.ORCID 0000-0003-0727-1244
Vishakha SabharwalDepartment of Pediatrics, Boston Medical Center, Boston, Massachusetts, USA.ORCID 0000-0002-5092-4442
Hyagriv N SimhanUniversity of Pittsburgh, Magee Womens Hospital, Pittsburgh, Pennsylvania, USA.
Geeta K SwamyDepartment of Obstetrics and Gynecology, Duke University, Durham, North Carolina, USA.ORCID 0000-0001-5092-6993
Kent D HeyborneUniversity of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA.
Baha M SibaiDepartment of Obstetrics and Gynecology, University of Texas Health Science Center at Houston-Children's Memorial Hermann Hospital, Houston, Texas, USA.
William A GrobmanDepartment of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois, USA.
Yasser Y El-SayedDepartment of Obstetrics and Gynecology, Stanford University, Stanford, California, USA.
Brian M CaseyDepartment of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Samuel ParryDepartment of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
George A MaconesDepartment of Womens Health, University of Texas at Austin, Austin, Texas, USA.

Funding

SARS-CoV-2 Vaccine Pregnancy RegistryU24HD036801 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI Rebecca Gersnoviez Clifton · 2021 to 2026
$39.2M
Enriching ECHO Cohorts with High-risk Pregnancies and Children with Health Challenges (Enriching ECHO)UH3OD035546 · OD · HACKENSACK UNIVERSITY MEDICAL CENTER · PI Judy Lynn Aschner, AARON HAMVAS · 2025 to 2026
$10.2M
Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD040485 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Noelia Milena Modad Zork · 2016 to 2026
$3.6M
NICHD Maternal Fetal Medicine Units NetworkUG1HD087192 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI Lorraine Dugoff · 2016 to 2026
$3.6M
NICHD Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD040544 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI Kelly S Gibson, Angela C. Ranzini · 2016 to 2026
$3.5M
Maternal-Fetal Medicine Units Network -- The Northwestern Study CenterUG1HD040512 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Lynn M Yee · 2016 to 2026
$3.4M
NICHD Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD040500 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI DWIGHT J ROUSE · 2016 to 2026
$3.4M
UofU Maternal-Fetal Medicine Units (MFMU) Network: Clinical CentersUG1HD034208 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Torri D Metz · 2016 to 2026
$3.4M
NICHD Maternal Fetal Medicine Units NetworkUG1HD027915 · NICHD · OHIO STATE UNIVERSITY · PI Maged Costantine · 2016 to 2026
$3.3M
UNC MFMU: Advancing Perinatal Health via Definitive, Multi-Site Clinical StudiesUG1HD040560 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI John M Thorp · 2016 to 2026
$3.3M
NICHD Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD087230 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HYAGRIV N SIMHAN · 2016 to 2026
$3.2M
NICHD Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD040545 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Hector Mendez-Figueroa · 2016 to 2026
$3.2M
CDC HHSNICHD NIH HHS U24 HD036801NICHD NIH HHS UG1 HD027869NICHD NIH HHS UG1 HD027915NICHD NIH HHS UG1 HD034116NICHD NIH HHS UG1 HD034208NICHD NIH HHS UG1 HD040485NICHD NIH HHS UG1 HD040500NICHD NIH HHS UG1 HD040512NICHD NIH HHS UG1 HD040544NICHD NIH HHS UG1 HD040545NICHD NIH HHS UG1 HD040560NICHD NIH HHS UG1 HD053097NICHD NIH HHS UG1 HD068258NICHD NIH HHS UG1 HD068268NICHD NIH HHS UG1 HD068282NICHD NIH HHS UG1 HD087192NICHD NIH HHS UG1 HD087230NICHD NIH HHS UG1 HD112063NIH HHS UH3 OD035546
6 · The paper itself

Abstract

In this study, a single hepatitis C virus (HCV) RNA at 2-6 months was sensitive and specific (86.7% and 95% confidence interval [CI], 62.1%-96.3% and 100% and 95% CI, 98.8%-100%, respectively) in identifying perinatal transmission of HCV. No cases of perinatal infection requiring treatment were missed.

Indexed as

HepacivirusHepatitis CInfectious Disease Transmission, VerticalPolymerase Chain ReactionPregnancy Complications, InfectiousAdultFemaleHumansInfantInfant, NewbornMalePregnancyRNA, ViralSensitivity and SpecificityRNA, ViralHCVhepatitis C virusPCRpediatric screeningperinatal transmission

Identifiers

PMID40653712
PMCPMC12285734

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.