Evidence map›Paper›PMID 40653702›Full record

Trial reportBJU international2025

Longer-term effects of intraoperative cone-beam computed tomography in percutaneous nephrolithotomy: 18-month retrospective randomised controlled trial analysis.

Chris A Suijker, Riemer A Kingma, Rosanne van Ee, Emelie N Steffens, Emanuela Altobelli, Mieke T J Bus, Igle J de Jong, Stijn Roemeling

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BJU international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Kidney stone disease: phenomenological perspectives.Medicine, health care, and philosophy · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chris A SuijkerDepartment of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0003-0715-2376
Riemer A KingmaDepartment of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0003-1648-0419
Rosanne van EeDepartment of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Emelie N SteffensDepartment of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Emanuela AltobelliDepartment of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Mieke T J BusDepartment of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Igle J de JongDepartment of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Stijn RoemelingDepartment of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the longer-term impact of intraoperative cone-beam computed tomography (CBCT) on stone-related morbidity after percutaneous nephrolithotomy (PCNL), since intraoperative CBCT allows for the detection and removal of residual fragments during the same procedure, improving stone clearance and thereby potentially diminishing stone-related morbidity. PATIENTS AND

methodsThis study was a retrospective analysis of a previously conducted single-centre randomised controlled trial at a tertiary complex endourology centre, in which patients were randomised intraoperatively to PCNL with intraoperative CBCT or conventional PCNL. We analysed 18-month follow-up data to assess differences in stone-related events (SREs), including re-interventions, emergency department visits, and hospital admissions. Stone-free rates and time to stone recurrence, as determined by follow-up CT scans, were also evaluated.

resultsThe CBCT group (n = 80) had a significantly lower detection rate of new or residual fragments >4 mm (hazard ratio [HR] 0.61, 95% confidence interval [CI] 0.38-0.97), with 29 (36%) cases during 18 months of follow-up compared to 40 (50%) cases in the conventional PCNL group (n = 80). The restricted mean (standard deviation [SD]) time to fragment detection was 420 (44) days in the CBCT group vs 318 (53) days in the conventional PCNL group. In the CBCT group, 15 (19%) cases experienced 26 SREs, compared to 23 (29%) cases with 39 SREs in the conventional PCNL group. The restricted mean (SD) time to SRE was 499 (26) days for CBCT cases, compared to 447 (39) days for conventional PCNL cases. The rate of SREs did not decrease significantly when comparing CBCT-PCNL to conventional PCNL (HR 0.61, 95% CI 0.32-1.17).

conclusionThis study found 10% fewer patients with SREs in the 18-month period after PCNL with intraoperative CBCT compared to conventional PCNL. This difference is likely due to the notable increase in stone-free rates following a single PCNL with intraoperative CBCT.

Indexed as

Cone-Beam Computed TomographyKidney CalculiNephrolithotomy, PercutaneousAdultAgedFemaleHumansIntraoperative CareMaleMiddle AgedRetrospective StudiesTreatment Outcomeintraoperative cone‐beam CTpercutaneous nephrolithotomyrandomised controlled trialresidual fragmentsstone‐related eventurolithiasis

Identifiers

PMID40653702
PMCPMC12522529

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.