Evidence map›Paper›PMID 40653645›Full record

ArticleInfluenza and other respiratory viruses2025

Effects of K-12 School District Nonpharmaceutical Interventions on Community-Level Prevalence of Acute Respiratory Infection During the COVID-19 Pandemic.

C He, M D Goss, D Norton, G Chen, A Uzicanin, J L Temte

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

C HeDepartment of Family Medicine and Community Health, University of Wisconsin, Madison, Wisconsin, USA.ORCID 0000-0002-3529-8906
M D GossDepartment of Family Medicine and Community Health, University of Wisconsin, Madison, Wisconsin, USA.ORCID 0000-0002-7062-1916
D NortonDepartment of Biostatistics and Medical Informatics, University of Wisconsin, Madison, Wisconsin, USA.
G ChenDepartment of Biostatistics and Medical Informatics, University of Wisconsin, Madison, Wisconsin, USA.
A UzicaninCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
J L TemteDepartment of Family Medicine and Community Health, University of Wisconsin, Madison, Wisconsin, USA.ORCID 0000-0001-7097-583X

Funding

Centers for Disease Control and Prevention (CDC) #5U01CK000542-02-00Centers for Disease Control and Prevention (CDC) #6U01CK000630-01-01NCEZID CDC HHS U01 CK000542NCEZID CDC HHS U01 CK000630School of Medicine and Public Health, University of Wisconsin-Madison
6 · The paper itself

Abstract

backgroundResponding to the COVID-19 pandemic, kindergarten through 12th grade schools implemented nonpharmaceutical interventions (NPIs). The effects of school-based NPIs on broader community levels of acute respiratory infection (ARI) have not been defined. We utilized an existing longitudinal cohort of households reporting weekly ARI cases to evaluate the effects of evolving school districtwide NPIs on ARI activity at eight transition points from December 2019 through October 2022.

methodsHousehold ARI data were reported through the GReat Oregon Child Absenteeism due to Respiratory Disease Study (ORCHARDS) Vaccine Effectiveness Study-a prospective cohort study based in the Oregon School District (OSD) (GROVES). Participating GROVES families completed weekly online surveys with respiratory illness updates. Mixed effects logistic regression was used to examine the association between eight school-related transition events during the COVID-19 pandemic and changes in the trajectory of ARI risk for GROVES family members, while accounting for family clusters. Transition events were assessed using a ±4-week window of community data.

resultsOpening schools with maximal NPIs (mandated masking and physical distancing, with hybrid education) was not associated with increased community ARI activity. The four transition events associated with significant ARI risk trajectory increases included summer breaks (June 2020, p = 0.001; June 2021, p = 0.002), and the start of school with mandatory masking only (September 2021, p < 0.001) or without NPIs (September 2022, p < 0.001).

conclusionsSchool-based NPI implementation was associated with reduced risks for community ARI activity. Enhanced surveillance platforms such as the weekly online surveys used in this study are valuable tools for better understanding and monitoring SARS-CoV-2 and respiratory virus transmission in schools and surrounding communities.

Indexed as

COVID-19Respiratory Tract InfectionsAdolescentChildChild, PreschoolFemaleHumansLongitudinal StudiesMaleOregonPrevalenceProspective StudiesSARS-CoV-2Schoolsacute respiratory infectionCOVID‐19K‐12 schoolsnonpharmaceutical interventionspublic health surveillancerespiratory virus transmissionSARS‐CoV‐2

Identifiers

PMID40653645
PMCPMC12256271

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.