ArticleNeurology and therapy2025
Characteristics of Postural Instability in Idiopathic Normal Pressure Hydrocephalus.
Article in Neurology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Reducing assessment timing in Tap-Test-positive patients with iNPH: a 24-hour strategy and the exploratory role of the Symbol-Digit Modalities Test in surgical triage.Fluids and barriers of the CNS · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
introductionIn patients with idiopathic normal pressure hydrocephalus (iNPH), the characteristics of static steady-state balance disturbance are not as well understood as those related to gait. This study aimed to investigate differences in center of pressure (COP) parameters between patients with iNPH and age-matched healthy controls.
methodsA total of 56 patients diagnosed with probable iNPH, who responded positively to cerebrospinal fluid tap test (CSFTT), along with 25 age-matched healthy controls, were enrolled. Prior to the CSFTT, COP measurements were taken using a force plate while participants stood quietly with eyes open (EO) and eyes closed (EC). We calculated the values of mediolateral (ML) and anteroposterior (AP) directions and ML/AP ratio in terms of the velocity of COP (vCOP), the standardized COP path length (Std_vCOP), and the peak power spectral density (PSD) at 0-0.5 Hz and 0.5-1.0 Hz. Additionally, we calculated the average distance from the COP center (Dist_COP) and the base of support (BOS). A Mann-Whitney U test with Bonferroni correction was used to compare differences between healthy controls and patients with iNPH under each visual condition (EO vs. EC).
resultsThere were no significant differences in gender, age, height, and weight between the healthy controls and the patients with iNPH. Patients with iNPH demonstrated greater spontaneous sway in the ML direction of vCOP (p < 0.001), increased variability in both ML and AP directions of Std_vCOP (p < 0.001 for both), a larger Dist_COP (p < 0.001) and BOS (p < 0.001) in the EC condition. Under the EO condition, patients with iNPH exhibited a significantly higher ML/AP ratio (p < 0.001) and larger BOS (p < 0.001). Furthermore, peak PSD at 0-0.5 Hz, reflecting low-frequency oscillations, was more pronounced in the ML direction and in the ML/AP ratio (p < 0.001 for both under EO), as well as in the AP direction (p < 0.001 under EC) in patients with iNPH. However, no significant differences were observed in the high-frequency oscillations (0.5-1.0 Hz).
conclusionsThese findings suggest that patients with iNPH exhibit distinct COP patterns, particularly greater variability in the ML direction during quiet standing. In contrast, the AP direction appears to be more influenced by visual conditions when compared to healthy controls. This result highlights the potential need for tailored balance training in patients with iNPH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.