Evidence map›Paper›PMID 40653563›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Effect of aromatherapy massage with lavender essential oil on sleep quality, pain, and mental and psychiatric disorders among breast cancer patients undergoing chemotherapy: a randomized controlled trial.

Fengxian Zhang, Lin Cheng, Sifan Qin, Liwei Wang, Yun Liu, Yuxiu Liu, Jinhong Yang, Shirong Fang, Na An, Yufeng Zhang and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06338527 (Effects of Aromatherapy on Sleep Quality and Anxiety in Patients Undergoing Chemotherapy for Breast Cancer), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06338527 naunknown statusnot on this map

Effects of Aromatherapy on Sleep Quality and Anxiety in Patients Undergoing Chemotherapy for Breast Cancer

TypeinterventionalSponsorWeifang Medical UniversityRan2024 to 2024Enrolled90ConditionsSleep Quality, AnxietyArmsAromatherapy, No intervention
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Need for transparent reporting of aromatherapy intervention.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Fengxian Zhang *Shandong Second Medical University, Weifang, Shandong, China.
Lin Cheng *Weifang People's Hospital, Weifang, Shandong, China.
Sifan QinShandong Second Medical University, Weifang, Shandong, China.
Liwei WangShandong Second Medical University, Weifang, Shandong, China.
Yun LiuShandong Second Medical University, Weifang, Shandong, China.
Yuxiu LiuShandong Second Medical University, Weifang, Shandong, China.
Jinhong YangWeifang People's Hospital, Weifang, Shandong, China.
Shirong FangWeifang People's Hospital, Weifang, Shandong, China.
Na AnWeifang People's Hospital, Weifang, Shandong, China.
Yufeng ZhangWeifang People's Hospital, Weifang, Shandong, China.
Jiang LiuXiangya School of Nursing, Central South University, Changsha, China. Time1987fx@163.com.ORCID http://orcid.org/0000-0002-0126-3377

Funding

National Key Research and Development Program of China 2022YFC3601603National Natural Science Foundation of China 72374224
6 · The paper itself

Abstract

objectivesTo assess the effects of aromatherapy massage on sleep quality and mental and psychological disorders in breast cancer survivors (BCS) undergoing chemotherapy.

methodsThe study was a prospective, double-blind, randomized, placebo-controlled trial. Eligible breast cancer patients were enrolled in this study. Participants were randomly assigned to either the intervention group (received lavender aromatherapy) or the placebo group (received sweet almond oil massage). Aromatherapists focused their massage on specific areas of the body (from the lumbosacral area to the soles of the feet, and then from the shoulders to the palms of the hands). From baseline to four weeks after the intervention, the Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality, the Visual Analog Scale (VAS) was used to assess pain response, the Mini-Mental State Examination (MMSE) score was used to assess cognitive function, the Beck Anxiety Inventory (BAI) was used to assess anxiety, and the Beck Depression Inventory Second Version (BDI-II) was used to assess depression in patients. All statistical analyses were conducted using STATA software (version 16.0), with a P-value < 0.05 considered statistically significant.

resultsUltimately, a total of 96 participants were divided into the intervention group (n = 47) and the placebo group (n = 51). The baseline characteristics were statistically comparable between the two groups. Statistically significant differences were observed in sleep quality scores (7.51 ± 2.90 vs 9.71 ± 2.67, P < 0.001), anxiety scores (20.26 ± 6.73 vs 24.10 ± 6.46, P = 0.005), and pain response (6.66 ± 1.45 vs 7.41 ± 1.19, P = 0.006) of the intervention group compared to the control group at the 4th week post-intervention. However, there was no significant difference in depression scores (29.43 ± 7.17 vs 30.88 ± 6.26, P = 0.286) and cognitive function scores (28.06 ± 1.55 vs 27.51 ± 1.97, P = 0.128) between the two groups.

conclusionAroma massage with lavender essential oil may have a positive effect for BCS undergoing chemotherapy and warrants further promotion.

trial registrationThis trial was registered at www. CLINICALTRIALS: gov (Registration Number: NCT06338527, Registration Date: March 28, 2024).

Indexed as

AromatherapyBreast NeoplasmsCancer PainMassageMental DisordersOils, VolatilePlant OilsAdultAgedAntineoplastic AgentsAnxietyDepressionDouble-Blind MethodFemaleHumansLavandulaAntineoplastic Agentslavender oilOils, VolatilePlant OilsAnxietyAromatherapyBreast cancerCognitive functionDepressionPainSleep quality

Identifiers

PMID40653563

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.