The Psychology of Social Isolation and Loneliness in Later Life.

Lee Kehoe, Kimberly A Van Orden

Abstract readReview

In one paragraph

Review in Clinics in geriatric medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lee KehoeDepartment of Psychiatry, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, NY 14642, USA.

Kimberly A Van OrdenDepartment of Psychiatry, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, NY 14642, USA. Electronic address: Kimberly_vanorden@urmc.rochester.edu.

Funding

Institutional Career Development CoreKL2TR001999 · NCATS · UNIVERSITY OF ROCHESTER · PI XIAO, JIN · 2016 to 2024

$5.2M

Rochester Roybal Center for Social Ties and Aging ResearchP30AG064103 · NIA · UNIVERSITY OF ROCHESTER · PI VAN ORDEN, KIMBERLY ALLISON · 2019 to 2023

$3.6M

Brain and Behavioral Mechanisms Linking Loneliness and Social Isolation with Accelerated Cognitive Aging and Alzheimer's Disease and Related DementiasK24AG084885 · NIA · UNIVERSITY OF ROCHESTER · PI Kimberly Allison Van Orden · 2024 to 2026

$493k

NCATS NIH HHS KL2 TR001999NIA NIH HHS K24 AG084885NIA NIH HHS P30 AG064103

6 · The paper itself

Abstract

This scoping review examines the psychological implications of social isolation and loneliness (SIL) in older adults, emphasizing risk and resilience factors. SIL is linked to mental health issues (depression, anxiety, and cognitive decline) and physical health risks (cardiovascular disease, mortality). The review proposes a conceptual model highlighting the balance between protective factors (emotional regulation, wisdom) and vulnerabilities (role transitions, chronic illness) that influence SIL's chronicity. Interventions should focus on prevention during life transitions, disrupting chronic loneliness, and mitigating health impacts. The review underscores the need for targeted-strategies to bolster adaptive capacity in older adults.

Indexed as

AgingLonelinessSocial IsolationAgedHumansAdaptive capacityOlder adultsPsychological implicationsSocial isolation and loneliness

Identifiers

PMID40653337

DOI10.1016/j.cger.2025.04.004

PMCPMC13527821

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.