ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2025
Temporal trends in tuberculosis and time from enrolment in care to antiretroviral therapy initiation: A multicountry cohort study from Latin America.
Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Trends in Incidence and Risk Factors of HIV-Associated Disseminated Histoplasmosis in the Americas: An Observational Cohort Study.Journal of the International AIDS Society · 2026Observational
- The Caribbean, Central and South America Network for HIV Epidemiology: 20 Years of HIV Research in the Region.Journal of the International AIDS Society · 2026Article
- Generating synthetic multi-national longitudinal cohorts for clinically grounded HIV research.Nature communications · 2026Article
- Generating Synthetic Multi-national Longitudinal Cohorts for Clinically Grounded HIV Research.medRxiv : the preprint server for health sciences · 2025Article
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Authors and funding
14 authors.
Funding
Abstract
backgroundHIV treatment guidelines have evolved to recommend rapid antiretroviral therapy (ART) initiation. Data on the impact of these changes in the Americas region are scarce.
methodsThis study included data from CCASAnet sites in Brazil, Haiti, Honduras, Mexico, and Peru. ART-naïve adults who started ART from 2006 to 2022 were included. Trends in CD4 count, tuberculosis (TB), and treatment initiation were described using cumulative probability and logistic and Cox regression models.
findingsTotal 29,881 PLWH met inclusion criteria; 2179 (7.3%) were diagnosed with prevalent TB and 379 (1.2%) with incident TB within six months after ART initiation. For individuals without TB, enrolment CD4 count increased from 160 to 320 cells/mm
conclusionsTime to ART initiation has decreased in the CCASAnet consortium, with the majority of PLWH now starting ART within a week after enrolment. There has also been a decline in the prevalence and incidence of concurrent TB disease.
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