Evidence map›Paper›PMID 40652980›Full record

Observational studyJournal of affective disorders2025

Associations between sleep, obesity, and mental health in adolescents: Understanding sex-specific vulnerabilities.

Orsolya Kiss, Anya Harkness, Eva M Müller-Oehring, Jason M Nagata, Fiona C Baker

Abstract readObservational Study
In one paragraph

Observational study in Journal of affective disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Orsolya KissCenter for Health Sciences, SRI International, Menlo Park, CA, USA. Electronic address: orsolya.kiss@sri.com.
Anya HarknessCenter for Health Sciences, SRI International, Menlo Park, CA, USA.
Eva M Müller-OehringCenter for Health Sciences, SRI International, Menlo Park, CA, USA; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Jason M NagataDivision of Adolescent and Young Adult Medicine, Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA.
Fiona C BakerCenter for Health Sciences, SRI International, Menlo Park, CA, USA; School of Physiology, University of the Witwatersrand, Johannesburg, South Africa.

Funding

ABCD-USA Consortium: Coordinating CenterU24DA041147 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SANDRA A BROWN, TERRY L. JERNIGAN · 2015 to 2026
$54.7M
ABCD-USA Consortium: Data Analysis, Informatics and Resource CenterU24DA041123 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANDERS M DALE · 2015 to 2026
$51.5M
Adolescent Substance Use Initiation: Disentangling neurocognitive risks from consequences using longitudinal and genetically-informed methodsU01DA041120 · NIDA · UNIVERSITY OF MINNESOTA · PI Monica Luciana, Sylia Wilson · 2015 to 2026
$34.5M
ABCD-USA Consortium: Research ProjectU01DA041089 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus, Susan F. Tapert · 2015 to 2026
$31.7M
Prospective Research Studies of Maturation (PRISM)- Research ProjectU01DA041134 · NIDA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI ERIN MCGLADE, PERRY FRANKLIN RENSHAW · 2015 to 2026
$29.2M
ABCD-USA CONSORTIUM: RESEARCH PROJECTU01DA041048 · NIDA · CHILDREN'S HOSPITAL OF LOS ANGELES · PI Megan Marie Herting, ELIZABETH R SOWELL · 2015 to 2026
$28.7M
ABCD-USA Consortium: Research ProjectU01DA041106 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mary M Heitzeg, Chandra Sekhar Sripada · 2015 to 2026
$24.9M
FIU-ABCD: Pathways and Mechanisms to Addiction in the Latino Youth of South FloridaU01DA041156 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI Raul Gonzalez, Angela R Laird · 2015 to 2026
$22.8M
ABCD-USA Consortium: Research ProjectU01DA041148 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Damien A Fair, Rebekah S Huber · 2015 to 2026
$22.3M
ABCD-USA: NYC Research ProjectU01DA041174 · NIDA · YALE UNIVERSITY · PI Arielle Ryan Baskin-Sommers, Betty J Casey · 2015 to 2026
$19.7M
Adolescent Brain Cognitive Development (ABCD) Prospective Research in Studies of Maturation (PRISM) ConsortiumU01DA041117 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI LINDA CHANG, THOMAS M ERNST · 2015 to 2026
$19.5M
15/21 ABCD-USA Consortium: Research Project Site at LIBRU01DA050989 · NIDA · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI ROBIN L AUPPERLE, MARTIN P. PAULUS · 2020 to 2026
$14.7M
NHLBI NIH HHS K08 HL159350NIDA NIH HHS U01 DA041022NIDA NIH HHS U01 DA041025NIDA NIH HHS U01 DA041028NIDA NIH HHS U01 DA041048NIDA NIH HHS U01 DA041089NIDA NIH HHS U01 DA041093NIDA NIH HHS U01 DA041106NIDA NIH HHS U01 DA041117NIDA NIH HHS U01 DA041120NIDA NIH HHS U01 DA041134NIDA NIH HHS U01 DA041148NIDA NIH HHS U01 DA041156NIDA NIH HHS U01 DA041174NIDA NIH HHS U01 DA050987NIDA NIH HHS U01 DA050988NIDA NIH HHS U01 DA050989NIDA NIH HHS U01 DA051016NIDA NIH HHS U01 DA051018NIDA NIH HHS U01 DA051037NIDA NIH HHS U01 DA051038NIDA NIH HHS U01 DA051039NIDA NIH HHS U24 DA041123NIDA NIH HHS U24 DA041147NIMH NIH HHS R01 MH128959NIMH NIH HHS R01 MH135492
6 · The paper itself

Abstract

introductionSleep disturbances and mental health challenges often arise during adolescence, with a greater prevalence among females and individuals experiencing obesity. In this study, we examined the intricate relationships between sleep problems, obesity, and biological sex, and their combined relationship with well-being in a large, diverse cohort of US adolescents.

methodsWe analyzed data from 7261 adolescents (Year 2: Mean age = 11.94 years, range: 10-14 years, 47.3 % female) participating in the ongoing Adolescent Brain Cognitive Development (ABCD) Study®. Sleep duration and sleep quality were determined from self-reported questionnaires. Internalizing and externalizing problems were assessed using the Child Behavior Checklist (caregiver-report) and the Brief Problem Monitor (youth-report). Positive affect was measured with the NIH Toolbox (youth-report). Regression models were used to investigate the associations between obesity (body mass index >95th percentile), sleep patterns, and mental health, while accounting for sex, age and socio-demographic variables.

resultsShorter sleep duration, poorer sleep quality, and experiencing obesity were associated with higher internalizing and externalizing problems. Longer sleep duration was associated with lower internalizing scores, but only among adolescents who were not experiencing obesity. Additionally, shorter sleep and poorer sleep quality were associated with lower positive affect, with stronger effects observed among adolescent females compared to males.

conclusionThis study reveals complex interactions between sleep, obesity, and mental health in adolescents, with notable sex differences. The findings emphasize the need for adolescent mental health interventions to address both sleep and obesity, while considering the distinct vulnerabilities associated with sex and obesity.

Indexed as

Pediatric ObesityPsychological Well-BeingSex FactorsSleepSleep Wake DisordersAdolescentAdolescent BehaviorBody Mass IndexChildFemaleHumansMaleMental HealthPrevalenceRegression AnalysisSurveys and QuestionnairesAdolescentsMental healthObesitySleepSleep problems

Identifiers

PMID40652980
PMCPMC12632359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.