ReviewPlant communications2025
WRKYs as regulatory hubs of secondary metabolic networks: Diverse inducers and distinct responses.
Review in Plant communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Molecular and transcriptional regulation of plant defense responses to aphid infestation.Stress biology · 2026Review
- The Convergence of Biotechnological Strategies in Medicinal Plants: From Individual Approaches Toward an Integrated Systems Framework.International journal of molecular sciences · 2026Review
- PlantInternational journal of molecular sciences · 2026Review
- Integrated Metabolomics and Transcriptomics Provided Novel Insights into the Biosynthetic Regulation of Phenolic Compounds inFoods (Basel, Switzerland) · 2026Article
- Integrated Transcriptomic and Metabolomic Analyses Reveal the Regulatory Drivers of Anthocyanin-Mediated Leaf Color Variation inInternational journal of molecular sciences · 2026Article
- The transcription factorHorticulture research · 2026Article
- ThePlants (Basel, Switzerland) · 2026Article
- Evolutionary Characteristics and Expression Patterns of theCurrent issues in molecular biology · 2026Article
- Molecular mechanism of ZmWRKY36 mediated maize resistance to Bipolaris maydis.BMC plant biology · 2026Article
- Study on differences in flavonoid synthesis inFrontiers in plant science · 2026Article
- The Ionic and Metabolic Response Mechanisms ofPlants (Basel, Switzerland) · 2025Article
- Identification of theFrontiers in plant science · 2025Article
- Advances in WRKY regulation of immune responses in medicinal plants.Frontiers in plant science · 2025Review
- Integrative transcriptome and metabolome evaluation of melanin biosynthesis inForestry research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
WRKY transcription factors (TFs) have been widely investigated for their roles in stress responses and plant development. Nevertheless, recent studies have revealed that WRKY TFs also exert important functions in the regulation of plant secondary metabolic networks, which are closely associated with crop resistance and quality. In this review, we comprehensively summarize how WRKYs are activated by various developmental and environmental cues to mediate distinct regulatory responses that control the biosynthesis of secondary metabolites such as flavonoids, carotenoids, and glucosinolates. We also examine the multi-layered modulation mediated by WRKYs, focusing on epigenetic regulation and post-translational modifications and highlighting their roles as regulatory hubs in secondary metabolism. Finally, we propose future research directions and discuss potential agricultural applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.