Evidence map›Paper›PMID 40652235›Full record

ArticleBMC pulmonary medicine2025

Pneumonia due to scrub typhus infection: a case report.

Zhiguang Wang, Yuhua Piao, Zhongjian An, Hongmei Piao

Abstract readCase Reports
In one paragraph

Article in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Nasopharyngeal Swabs forPathogens (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhiguang WangDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Yanbian University, Yanji, China.
Yuhua PiaoDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Yanbian University, Yanji, China.
Zhongjian AnDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Yanbian University, Yanji, China.
Hongmei PiaoDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Yanbian University, Yanji, China. piaohm1969@126.com.

Funding

Health Science and Technology Ability Improvement Program of Jilin Province Nos.2024A060
6 · The paper itself

Abstract

backgroundScrub typhus is an acute febrile illness caused by the rickettsial bacterium Orientia tsutsugamushi, transmitted to humans through infected mite bites. Patients typically present with sudden onset high fever, headache, myalgia, and eschar formation at the site of the bites. Respiratory symptoms, such as cough and shortness of breath, can also occur, especially in severe cases that lead to pneumonia or acute respiratory distress syndrome (ARDS). This report presents a case of scrub typhus pneumonia, diagnosed by metagenomic next-generation sequencing (mNGS) on bronchoalveolar lavage fluid(BALF). CASE PRESENTATION: A 58-year-old woman was admitted with cough, sputum production, and fever. Imaging revealed pneumonia. During hospitalization, bronchoscopy was performed to identify the causative pathogen. mNGS of the bronchoalveolar lavage fluid confirmed Orientia tsutsugamushi infection. Patient's pneumonia was improved after oral administration of doxycycline(100 mg two times daily) for 1 month.

conclusionThis report highlights the diagnostic challenges of scrub typhus-induced pneumonia and demonstrates usefulness and the advantages of mNGS in identifying rare pathogens.

Indexed as

Orientia tsutsugamushiPneumonia, BacterialScrub TyphusAnti-Bacterial AgentsBronchoalveolar Lavage FluidBronchoscopyDoxycyclineFemaleHigh-Throughput Nucleotide SequencingHumansMiddle AgedAnti-Bacterial AgentsDoxycyclineCase reportPneumoniaScrub typhus

Identifiers

PMID40652235
PMCPMC12255042

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.