Evidence map›Paper›PMID 40652146›Full record

ArticleAnnals of surgical oncology2025

The Effect of Valvulopathy on Adverse In-Hospital Outcomes After Partial and Radical Nephrectomy.

Calogero Catanzaro, Fabian Falkenbach, Andrea Marmiroli, Mattia Longoni, Quynh Chi Le, Michele Nicolazzini, Federico Polverino, Jordan A Goyal, Lorenzo Bianchi, Pietro Piazza and 11 more

Abstract read
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In one paragraph

Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Calogero CatanzaroCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada. calogero.catanzaro@studio.unibo.it.ORCID http://orcid.org/0009-0004-6265-5288
Fabian FalkenbachCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Andrea MarmiroliCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Mattia LongoniCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Quynh Chi LeCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Michele NicolazziniCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Federico PolverinoCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Jordan A GoyalCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Lorenzo BianchiDivision of Urology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Pietro PiazzaDivision of Urology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Angelo MottaranDivision of Urology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Fred SaadCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.
Shahrokh F ShariatDepartment of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Markus GraefenMartini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
Matteo FerroUniversità degli Studi di Milano, Milan, Italy.
Alberto BrigantiVita-Salute San Raffaele University, Milan, Italy.
Felix K H ChunDepartment of Urology, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.
Alessandro VolpeDivision of Urology, Department of Translational Medicine, University of Eastern Piedmont, Maggiore della Carità Hospital, Novara, Italy.
Nicola LongoDepartment of Neurosciences, Science of Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy.
Riccardo SchiavinaDivision of Urology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Pierre I KarakiewiczCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effect of valvulopathy on adverse in-hospital outcomes after partial nephrectomy (PN) and radical nephrectomy (RN) is unknown. PATIENTS AND

methodsDescriptive analyses, 1:2 propensity score matching and multivariable logistic and Poisson regression models were used to address National Inpatient Sample (2000-2019) patients with kidney cancer who underwent PN and RN, stratified according to presence or absence of valvulopathy.

resultsOverall, 38,673 patients underwent PN versus 92,072 RN. Of those, 836 (2.2%) and 2651 (2.9%) had valvulopathy, respectively. Valvulopathy rate decreased from 3.04 to 1.57% in PN patients (2000-2019, EAPC: -1.74%, p = 0.02), and from 2.97 to 2.28% in RN patients (2000-2019, EAPC: -0.94%, p = 0.01). RN patients with valvulopathy were older and carried a higher number of comorbidities than PN patients with valvulopathy. Valvulopathy in PN patients independently predicted higher rates of adverse in-hospital outcomes in 7 of 14 examined categories, with odds ratio (OR) ranging from 2.96 for cardiac complications to 2.35 for vascular complications and 1.78 for bleeding complications (all p < 0.05), but not in-hospital mortality (p > 0.05). Valvulopathy in RN patients independently predicted higher rates of adverse in-hospital outcomes in 9 of 14 examined categories, with OR ranging from 2.88 for cardiac complications to 1.83 for vascular complications and 1.43 for overall complications (all p < 0.05), but not in-hospital mortality (p > 0.05).

conclusionsPatients with valvulopathy treated with RN are generally older and present with more baseline comorbidities. In this population, RN is associated with a higher risk of adverse in-hospital outcomes compared with PN when examining the impact of valvulopathy on such outcomes.

Indexed as

Kidney NeoplasmsNephrectomyPostoperative ComplicationsAgedCarcinoma, Renal CellFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedPrognosisPropensity ScoreRetrospective StudiesRisk FactorsComplicationsKidney cancerNISPartial nephrectomyRadical nephrectomyValvulopathy

Identifiers

PMID40652146

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.