Evidence map›Paper›PMID 40652099›Full record

ArticleScientific reports2025

Deep learning algorithm for identifying osteopenia/osteoporosis using cervical radiography.

Koji Tamai, Keiho Imanishi, Masaki Terakawa, Masato Uematsu, Minori Kato, Hiromitsu Toyoda, Akinobu Suzuki, Shinji Takahashi, Akito Yabu, Yuta Sawada and 9 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Consensus statement on the application of artificial intelligence in osteoporosis screening and management: perspectives from the Asia-Pacific region.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Koji TamaiDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan. koji.tamai.707@gmail.com.
Keiho Imanishie-Growth Co, Kyoto, Japan.
Masaki TerakawaDepartment of Orthopedics, Osaka General Hospital of West Japan Railway Company, Osaka, Japan.
Masato UematsuDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Minori KatoDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Hiromitsu ToyodaDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Akinobu SuzukiDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Shinji TakahashiDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Akito YabuDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Yuta SawadaDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Masayoshi IwamaeDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Yuto KobayashiDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Yuki OkamuraDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Hiroshi TaniwakiDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Yuki KinoshitaDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Masatoshi HoshinoDepartment of Orthopaedic Surgery, Osaka Saiseikai Nakatsu Hospital, Osaka, Japan.
Hitoshi TabuchiDepartment of Technology and Design Thinking for Medicine, Hiroshima University, Hiroshima, Japan.
Hiroaki NakamuraDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.
Hidetomi TeraiDepartment of Orthopedics, Osaka Metropolitan University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to symptomatic gait imbalance and a high incidence of falls, patients with cervical disease-including degenerative cervical myelopathy-have a significantly increased risk of fragility fractures. To prevent such fractures in patients with cervical disease, treating osteoporosis is an important strategy. This study aimed to validate the diagnostic yield of a deep learning algorithm for detecting osteopenia/osteoporosis using cervical radiography and compare its diagnostic accuracy with that of spine surgeons. Samples were divided into training (n = 200) and test (n = 30) datasets. The deep learning algorithm, designed to detect T-scores of the femoral neck or lumbar spine <-1.0 using cervical radiography, was constructed using a convolutional neural network model. The number of correct diagnoses was compared between the algorithm and nine spine surgeons using the independent test dataset. The results indicated that the algorithm's diagnostic accuracy, sensitivity, and specificity in the independent test dataset were 0.800, 0.818, and 0.750, respectively. The rate of corrected answers by the deep learning algorithm was significantly higher than that of nine spine surgeons in the test dataset (80.0% vs. 60.6%; p = 0.032). In conclusion, the diagnostic yield of the algorithm was higher than that of spine surgeons.

Indexed as

Bone Diseases, MetabolicCervical VertebraeDeep LearningOsteoporosisRadiographyAgedAlgorithmsFemaleFemur NeckHumansLumbar VertebraeMaleMiddle AgedNeural Networks, ComputerSensitivity and SpecificityArtificial intelligenceCervicalDeep learningFragility fracturesOsteoporosisRadiography

Identifiers

PMID40652099
PMCPMC12255677

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.