ArticleNature communications2025
Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinoma.
Abstract read
In one paragraph
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Nuciferine Suppresses Inflammatory Hepatocarcinogenesis by Targeting cPLA2-Dependent Arachidonic Acid Metabolism.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Host-Derived Proteomic Profiling of Human and Canine Mammary Tumor Xenografts Identifies Enrichment of Lipid Metabolism-Related Pathways.Cell biochemistry and biophysics · 2026Article
- Androgen receptor drives lenvatinib resistance in hepatocellular carcinoma through transcriptional activation of EIF3I and a downstream ceRNA axis.Oncology letters · 2026Article
- High Expression of SAMM50 Indicates Poor Clinical Prognosis in Hepatocellular Carcinoma and Represents a Potential Novel Biomarker.Biological procedures online · 2026Article
- Context-dependent roles of lncRNA JPX in human cancers.Discover oncology · 2026Review
- Serum alpha-fetoprotein kinetics as a mechanistic biomarker for rAAV-TK/GCV efficacy in hepatocellular carcinoma.American journal of translational research · 2026Review
- Radiographic evidence of thymic involution in hepatocellular carcinoma: a propensity score-matched study in viral cirrhosis.Frontiers in immunology · 2026Article
- Clinical-pathological characteristics and prognosis of elderly primary liver cancer patients.American journal of cancer research · 2026Article
- Testosterone and Androgen Receptor in Cancers with Significant Sex Dimorphism in Incidence Rates and Survival.Cancers · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Zhilong Lin *Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID http://orcid.org/0009-0002-9425-3609
Xiaofei Liu *Department of Gastroenterology and Hepatology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Houwei Wang *Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Shumin Li *Department of Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Ziqiang Miao *Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jing YangDepartment of Gastroenterology and Hepatology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yuting ZhangDepartment of Pathology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Kai LeiCenter of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yifan WuDepartment of Gastroenterology and Hepatology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Youmei KangInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Ruoyin ZhengCenter of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Zonglin XieDepartment of Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yixi WenInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xiaoxue RenDepartment of Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Chunxiao LiuInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID http://orcid.org/0000-0002-8677-1943
Alfred Sze-Lok ChengSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Yubin XieInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID http://orcid.org/0000-0002-3566-4849
Shuling ChenInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Ming KuangCenter of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID http://orcid.org/0000-0002-7397-5779
Sui PengDepartment of Gastroenterology and Hepatology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. pengsui@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-7399-2579
Zhenwei PengClinical Trials Unit, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. pzhenw@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-0617-3805
Zihao DaiCenter of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. daizihao@mail2.sysu.edu.cn.ORCID http://orcid.org/0000-0002-8921-2389
Funding
National Natural Science Foundation of China (National Science Foundation of China) 82172047National Natural Science Foundation of China (National Science Foundation of China) 82373004
Abstract
Alpha-fetoprotein (AFP) is a classic biomarker for hepatocellular carcinoma (HCC). AFP-positive HCC (AFP
Indexed as
alpha-FetoproteinsArachidonic AcidCarcinoma, HepatocellularLiver NeoplasmsNeovascularization, PathologicReceptors, AndrogenAndrogen Receptor AntagonistsAnilidesAnimalsCell Line, TumorErbB ReceptorsFemaleGene Expression Regulation, NeoplasticHumansMaleMiceAFP protein, humanalpha-FetoproteinsAndrogen Receptor AntagonistsAnilidesArachidonic AcidAR protein, humanbicalutamideEGFR protein, humanErbB ReceptorsNitrilesPhenylurea CompoundsQuinolinesReceptors, AndrogenTosyl Compounds
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.