Evidence map›Paper›PMID 40651796›Full record

ArticleOsteoarthritis and cartilage2025

Research priorities for physical activity and exercise management of people with knee and hip osteoarthritis: A multi-stage international priority-setting study from the OARSI Rehabilitation Discussion Group.

Kim L Bennell, Rachel K Nelligan, Jesse J Pardo, Sarah Stratulate, Melanie A Holden, Belinda J Lawford, Louise M Thoma, Daniel K White, Elizabeth Wellsandt, Hiral Master and 6 more

Abstract read
In one paragraph

Article in Osteoarthritis and cartilage, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kim L BennellCentre for Health, Exercise and Sports Medicine, University of Melbourne, Victoria, Australia. Electronic address: k.bennell@unimelb.edu.au.
Rachel K NelliganCentre for Health, Exercise and Sports Medicine, University of Melbourne, Victoria, Australia. Electronic address: rachel.nelligan@unimelb.edu.au.
Jesse J PardoCentre for Health, Exercise and Sports Medicine, University of Melbourne, Victoria, Australia. Electronic address: jesse.pardo@unimelb.edu.au.
Sarah StratulateCentre for Health, Exercise and Sports Medicine, University of Melbourne, Victoria, Australia. Electronic address: sarah.stratulate@unimelb.edu.au.
Melanie A HoldenSchool of Medicine, Keele University, Staffordshire, United Kingdom. Electronic address: m.holden@keele.ac.uk.
Belinda J LawfordCentre for Health, Exercise and Sports Medicine, University of Melbourne, Victoria, Australia. Electronic address: belinda.lawford@unimelb.edu.au.
Louise M ThomaDepartment of Health Sciences, The University of North Carolina at Chapel Hill, NC, United States. Electronic address: louise_thoma@med.unc.edu.
Daniel K WhiteDepartment of Physical Therapy, University of Delaware, Delaware, United States. Electronic address: dkw@udel.edu.
Elizabeth WellsandtDepartment of Health and Rehabilitation Sciences, University of Nebraska Medical Center, Nebraska, United States. Electronic address: elizabeth.wellsandt@unmc.edu.
Hiral MasterVanderbilt University Medical Center, Vanderbilt University, TN, United States. Electronic address: hiralmaster21@gmail.com.
Jesper Bie LarsenDepartment of Health Science and Technology, Aalborg University, Jutland, Denmark. Electronic address: jbl@hst.aau.dk.
Kate ButtonSchool of Healthcare Sciences, Cardiff University, Cardiff, United Kingdom. Electronic address: buttonk@cardiff.ac.uk.
Natalie J CollinsSchool of Health and Rehabilitation Sciences, The University of Queensland, Queensland, Australia. Electronic address: n.collins1@uq.edu.au.
Søren T SkouThe Research and Implementation Unit PROgrez, Department of Physiotherapy and Occupational Therapy, Næstved-Slagelse-Ringsted Hospitals, Slagelse, Denmark; Center for Muscle and Joint Health, University of Southern Denmark, Odense, Denmark. Electronic address: stskou@health.sdu.dk.
Yves HenrotinDepartment of Physical Activity and Rehabilitation, musculoSkeletal Innovative research lab (mSKIL), University of Liège, Liège; Department of Physical Therapy and Rehabilitation, Vivalia, Marche-en-Famenne, Belguim. Electronic address: yhenrotin@uliege.be.
Rana S HinmanCentre for Health, Exercise and Sports Medicine, University of Melbourne, Victoria, Australia. Electronic address: ranash@unimelb.edu.au.

Funding

Tracking and Evaluation CoreU54GM115458 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI ZHANG, YING · 2016 to 2025
$42.8M
NIGMS NIH HHS U54 GM115458
6 · The paper itself

Abstract

objectiveTo identify research priorities for physical activity and exercise management of knee and hip osteoarthritis (OA).

designWe used a multi-stage process involving an international multi-disciplinary panel of 276 experts (150 consumers, 69 clinicians spanning 5 disciplines, 54 researchers, and 3 funder/consumer organisation representatives) from 26 countries. The process included: 1) compiling a list of unanswered research questions from existing research; 2) assembling the panel and generating additional questions from members via an online survey; 3) consolidating research questions (eg. removing duplicates); 4) scoring questions for priority by the panel on an 11-point numeric rating scale (0='not a priority at all; 10='highest priority') via another online survey; and 5) ranking the top 20 priority questions by the panel via an online discrete choice experiment (1000Minds).

resultsA list of 61 research questions was compiled from the literature and the panel generated an additional 346 questions. Following consolidation, 178 questions remained and were scored by 150 of the original panelists (54%), with mean priority scores from 5.0 to 8.4. 153 (55%) panelists completed the discrete choice experiment. The top three research priorities were: 1) investigating the impact of physical activity and exercise on delaying/avoiding joint replacement, 2) developing effective interventions to promote long-term exercise adherence, and 3) stratifying people to the most appropriate form of exercise support.

conclusionWe identified research priorities about physical activity and exercise management of knee and hip OA. These will guide the international research agenda with the aim of improving outcomes for people with OA.

Indexed as

Biomedical ResearchExerciseExercise TherapyOsteoarthritis, HipOsteoarthritis, KneeHumansResearchExerciseHipKneeOsteoarthritisPhysical activityRehabilitationResearch prioritiesSurvey

Identifiers

PMID40651796
PMCPMC12723755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.