Evidence map›Paper›PMID 40651651›Full record

ArticleEnvironmental pollution (Barking, Essex : 1987)2025

Current emission vs. legacy organic pollutants: Assessing the extent to which the eco-exposome of caged fish reflects external exposure.

Janek P Dann, Gerald T Ankley, Brett R Blackwell, Beate I Escher, Annika Jahnke, Kathleen M Jensen, Correne Jenson, Martin Krauss, Stefan Scholz, Theo Wernicke and 1 more

Abstract read
In one paragraph

Article in Environmental pollution (Barking, Essex : 1987), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Janek P DannHelmholtz Centre for Environmental Research GmbH - UFZ, Leipzig, 04318, Germany; Institute of Ecology, Diversity and Evolution, Goethe University Frankfurt, Frankfurt am Main, 60438, Germany.
Gerald T AnkleyUnited States Environmental Protection Agency, Office of Research and Development, Great Lakes Toxicology and Ecology Division (GLTED), 6201 Congdon Blvd, Duluth, 55804, MN, USA.
Brett R BlackwellUnited States Environmental Protection Agency, Office of Research and Development, Great Lakes Toxicology and Ecology Division (GLTED), 6201 Congdon Blvd, Duluth, 55804, MN, USA.
Beate I EscherHelmholtz Centre for Environmental Research GmbH - UFZ, Leipzig, 04318, Germany; Environmental Toxicology, Department of Geosciences, Eberhard Karls University Tübingen, Tübingen, 72076, Germany.
Annika JahnkeHelmholtz Centre for Environmental Research GmbH - UFZ, Leipzig, 04318, Germany; Institute for Environmental Research, RWTH Aachen University, Aachen, 52074, Germany.
Kathleen M JensenUnited States Environmental Protection Agency, Office of Research and Development, Great Lakes Toxicology and Ecology Division (GLTED), 6201 Congdon Blvd, Duluth, 55804, MN, USA.
Correne JensonUnited States Environmental Protection Agency, Office of Research and Development, Great Lakes Toxicology and Ecology Division (GLTED), 6201 Congdon Blvd, Duluth, 55804, MN, USA.
Martin KraussHelmholtz Centre for Environmental Research GmbH - UFZ, Leipzig, 04318, Germany. Electronic address: martin.krauss@ufz.de.
Stefan ScholzHelmholtz Centre for Environmental Research GmbH - UFZ, Leipzig, 04318, Germany.
Theo WernickeUmweltbundesamt, UBA, Dessau-Roßlau, 06844, Germany.
Werner BrackHelmholtz Centre for Environmental Research GmbH - UFZ, Leipzig, 04318, Germany; Institute of Ecology, Diversity and Evolution, Goethe University Frankfurt, Frankfurt am Main, 60438, Germany.

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

The eco-exposome represents the totality of chemicals present in an organism. To understand how internal exposure of fish relates to chemicals originating from external media (water, sediment), we conducted a 21-d caging study using fathead minnow (Pimephales promelas, FHM) as model species. Four sites in/at Lake Superior were chosen that reflect sources of two broad groups of environmental contaminants: Two pond sites with a legacy contamination by persistent organic pollutants (POPs), one site close to a wastewater treatment plant (WWTP) outlet showing more recent and regularly discharged compounds, and one creek expected to show a mixed contamination from both compound groups. We determined total water concentrations, freely dissolved concentrations in sediment pore water, and the FHM's body burden of organic micropollutants after 2 and 21 d of exposure. Of the 456 target compounds analyzed in FHM, 123 were quantified in water, 165 in sediment and 100 in FHM tissue samples. Chemical profiles and concentrations at the different study locations varied according to their classification as legacy or recently contaminated sites, with the site impacted by the WWTP showing the highest overall concentrations. Only 77 substances quantified in FHM were also detected in water and/or sediment and after applying additional quality and consistency measures, 37 of the 100 substances detected in FHM could not be directly linked to water and/or sediment. Therefore, chemical concentrations in water and sediment cannot simply predict the eco-exposome in fish, which underscores the need of body burden analysis to comprehensively understand an organism's exposure.

Indexed as

CyprinidaeEnvironmental ExposureEnvironmental MonitoringPersistent Organic PollutantsWater Pollutants, ChemicalAnimalsGeologic SedimentsLakesPersistent Organic PollutantsWater Pollutants, ChemicalAquatic ecosystemsContamination patternsEco-exposomeFishMicropollutantsTarget screening

Identifiers

PMID40651651
PMCPMC12915642

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.