Evidence map›Paper›PMID 40651495›Full record

Trial reportJournal of the American Medical Directors Association2025

A Cross-Lagged Panel Model Testing the Impact of Physical Activity During Hospitalization on 1- and 6-Month Discharge Physical Activity and Adverse Events Among Older Adults With Dementia.

Shijun Zhu, Barbara Resnick, Marie Boltz, Elizabeth Galik, Rachel McPherson, Ashley Kuzmik, Chris Wells, Soyeon Shim, Eunji Lee

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Medical Directors Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shijun ZhuUniversity of Maryland School of Nursing, Baltimore, MD, USA. Electronic address: Shijun.zhu@umaryland.edu.
Barbara ResnickUniversity of Maryland School of Nursing, Baltimore, MD, USA.
Marie BoltzPenn State University, College of Nursing, University Park, PA, USA.
Elizabeth GalikUniversity of Maryland School of Nursing, Baltimore, MD, USA.
Rachel McPhersonUniversity of Maryland School of Nursing, Baltimore, MD, USA.
Ashley KuzmikPenn State University, College of Nursing, University Park, PA, USA.
Chris WellsUniversity of Maryland Medical Center, University of Maryland School of Nursing, Baltimore, MD, USA.
Soyeon ShimUniversity of Maryland School of Nursing, Baltimore, MD, USA.
Eunji LeeUniversity of Maryland School of Nursing, Baltimore, MD, USA.

Funding

Testing the Efficacy of FFC-AC-EIT in Patients with Alzheimers Disease and Related DementiasR01AG065338 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI BOLTZ, MARIE, RESNICK, BARBARA · 2020 to 2024
$2.4M
NIA NIH HHS R01 AG065338
6 · The paper itself

Abstract

objectiveThe objective of this study was to examine the effects of physical activity during hospital stay on falls, emergency room visits, and rehospitalizations among older patients with dementia at 1 and 6 months post discharge.

designThis is a secondary data analysis. Bidirectional analysis using panel data from a cluster randomized clinical trial was utilized. SETTING AND

participantsThe sample comprised 455 older adults with dementia from a clustered randomized clinical trial among 12 hospitals in 2 east coast states.

methodsThe bidirectional relationships between physical activity at 1 and 6 months and falls, emergency room visits, and rehospitalizations at 1 and 6 months post discharge and their relations with physical activity at discharge were assessed using cross-lagged panel models, accounting for the autoregression of physical activity and adverse events over time. Age, race, gender, cognitive status, admission location, comorbidity, and intervention groups were controlled in the modeling.

resultsPhysical activity at hospitalization discharge showed autoregressive associations for the 3 time points. Patients with a higher level of physical activity at discharge had a lower chance of falling (β = -0.250, SE = 0.094, OR = 0.779, P = .008) and rehospitalizations (β = -0.228, SE = 0.092, OR = 0.796, P = .013) within 1 month post discharge. Falls, emergency room visits, or rehospitalizations at 1 month were not significantly associated with physical activity, or any adverse events at 6 months. CONCLUSIONS AND IMPLICATIONS: The findings from this study highlighted the significance and value of engaging older adults, particularly those living with dementia, in physical activity when hospitalized, as this reduced the likelihood of adverse events such as falls and rehospitalization at least in the first month post discharge.

Indexed as

Accidental FallsDementiaExerciseHospitalizationPatient DischargeAgedAged, 80 and overEmergency Service, HospitalFemaleHumansMalePatient Readmissionadverse eventsCross-lagged panel modelphysical activity

Identifiers

PMID40651495
PMCPMC12258953

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.