Evidence map›Paper›PMID 40651012›Full record

ArticleFuture oncology (London, England)2025

Prognostic value of Naples prognostic score for locally advanced gastric cancer after neoadjuvant chemoimmunotherapy.

Xiong Sun, Tuo Ruan, Yao Lin, Chengguo Li, Qian Shen, Tianhao Li, Jianing Ding, Yuping Yin, Kaixiong Tao

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Article in Future oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Xiong SunDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Tuo RuanDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Yao LinDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Chengguo LiDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Qian ShenDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Tianhao LiDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Jianing DingDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Yuping YinDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Kaixiong TaoDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe parameters of the Naples prognostic score (NPS) include albumin, total cholesterol, neutrophil-lymphocyte ratio, and lymphocyte-monocyte ratio. This study aimed to investigate the prognostic value of preoperative NPS in locally advanced gastric cancer(LAGC) patients underwent radical resection after neoadjuvant chemoimmunotherapy (NCIT). RESEARCH DESIGN AND

methodsThe NPS was calculated and patients were then divided into two groups according to their NPS values as follows: NPS = 0-2 (group 1), NPS = 3-4 (group 2). Univariate and multivariate Cox analysis were used to identify independent prognostic factors associated with overall survival (OS), and time-dependent receiver operating characteristic (t-ROC) curves were carried to evaluate the discriminatory capacity of the prognostic scoring systems.

resultsA total of 117 patients were included in this study. The 1- and 2-year OS rates in group 1 were 100.0% and 95.7%, group 2 exhibited rates of 95.7% and 84.4%. Multivariate cox analysis demonstrated that NPS was an independent prognostic factor of OS (

conclusionsNPS is a significant prognostic indicator and can be a reliable predictor of survival in LAGC patients underwent radical resection after NCIT.

Indexed as

Stomach NeoplasmsAdultAgedAntineoplastic Combined Chemotherapy ProtocolsCholesterolFemaleGastrectomyHumansImmunotherapyLymphocytesMaleMiddle AgedMonocytesNeoadjuvant TherapyNeoplasm StagingNeutrophilsCholesterolinflammationLocally advanced gastric cancermalnutritionNaples prognostic scoreneoadjuvant chemoimmunotherapyprognosis

Identifiers

PMID40651012
PMCPMC12344804

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