ArticleSleep & breathing = Schlaf & Atmung2025
The effect of continuous positive airway pressure on nocturnal blood pressure among obstructive sleep apnea-hypopnea syndrome patients.
Article in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and safety of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea: an overview of systematic reviews and meta analyses.Frontiers in medicine · 2026Pooled it
- [Association Between Obstructive Sleep Apnea and Behavioral Problems in Children].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeFew articles focus on the effect of CPAP on the nocturnal blood pressure in OSA patients. This study aims to evaluate the effects of continuous positive airway pressure (CPAP) therapy on nocturnal blood pressure in individuals with obstructive sleep apnea-hypopnea syndrome (OSAHS), which fills the research gap. Additionally, differences in nocturnal blood pressure measurements before and after CPAP therapy were analyzed across varying disease severities.
methodsA total of 80 individuals with newly diagnosed OSAHS who sought care at the Sleep Respiratory Disease Diagnosis and Treatment Center at West China Fourth Hospital of Sichuan University between December 2022 and June 2023 were included in this study. All participants completed a single night of CPAP therapy, administered from 10:00 PM on day 1 to 6:00 AM on day 2, during which nocturnal blood pressure measurements were assessed using pulse transit time.
resultsFollowing CPAP therapy, significant reductions were observed in the mean nocturnal diastolic blood pressure (nDBP) [(78.40 ± 13.06) vs. (74.03 ± 9.90) mmHg] and the nocturnal blood pressure fluctuation index (NBPFI) [(21.38 ± 19.95) vs. (5.81 ± 5.40) n/h] (p < 0.05). However, no significant difference was noted in the mean nocturnal systolic blood pressure (p > 0.05). Subgroup analysis based on disease severity: The reductions in nDBP [(6.16 ± 11.89) vs. (-0.32 ± 12.43) mmHg, p < 0.05] and nocturnal blood pressure fluctuation [(20.48 ± 19.05) vs. (2.59 ± 4.44) n/h, p < 0.05] were significantly greater in the severe group compared to the mild-to-moderate group.
conclusionThe findings suggested that CPAP therapy could potentially contribute to reductions in nDBP and the NBPFI in individuals with OSAHS, with more noticeable effects in patients with severe OSAHS.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.