Evidence map›Paper›PMID 40650716›Full record

Trial reportJournal of nephrology2025

Impact of almond milk fortified with vitamin D3-loaded soy protein nanoparticles on serum 25(OH)D3 concentrations in adults with CKD: a pilot double-blind randomized controlled trial.

Li-Ying Kuo, Blanca Nuria Casta Neda, Yangyi E Luo, Jiyan Aslan Ceylan, Juan E Andrade, Jeanette M Andrade

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Li-Ying KuoDepartment of Food Science and Human Nutrition, University of Florida, Gainesville, FL, 32606, USA.
Blanca Nuria Casta NedaDepartment of Food Science and Human Nutrition, University of Florida, Gainesville, FL, 32606, USA.
Yangyi E LuoDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, 32606, USA.
Jiyan Aslan CeylanDepartment of Food Science and Human Nutrition, University of Florida, Gainesville, FL, 32606, USA.ORCID http://orcid.org/0000-0003-1649-3586
Juan E AndradeDepartment of Food Science and Human Nutrition, University of Florida, Gainesville, FL, 32606, USA.ORCID http://orcid.org/0000-0003-2349-9169
Jeanette M AndradeDepartment of Food Science and Human Nutrition, University of Florida, Gainesville, FL, 32606, USA. jandrade1@ufl.edu.ORCID http://orcid.org/0000-0003-4452-4546

Funding

Scientific and Technological Research Council of Turkey 1059B192301773
6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) impairs the activation of vitamin D, leading to deficiencies that exacerbate disease progression and metabolic complications. This pilot study investigated the effects of consuming almond milk fortified with vitamin D

methodsA 21-day, double-blind randomized controlled pilot study was conducted. Participants (n = 18) were randomly assigned to consume 4 oz (118 ml) of almond milk daily with 4000 IU of vitamin D

resultsFrom baseline to end of intervention, there was a significant decrease in serum 25(OH)D3 in the control group (49.2 ± 23.3 nmol/L to 44.5 ± 25.6 nmol/L; p < 0.05). In the intervention group, there was a significant increase in 25(OH)D3 (33.0 ± 15.8 nmol/L to 36.4 ± 15.8 nmol/L; p < 0.05). A significant time × treatment interaction (p < 0.01) was observed, with the intervention group showing a marked increase in serum 25(OH)D

conclusionThe consumption of almond milk fortified with vitamin D

Indexed as

CalcifediolCholecalciferolFood, FortifiedNanoparticlesPrunus dulcisRenal Insufficiency, ChronicSoybean ProteinsAdultAgedBiomarkersCalciumDouble-Blind MethodFemaleHumansMaleMiddle AgedBiomarkersCalcifediolCalciumCholecalciferolParathyroid HormonePTH protein, humanSoybean ProteinsAlmond MilkChronic Kidney DiseaseNanoparticlesVitamin D

Identifiers

PMID40650716

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.