Evidence map›Paper›PMID 40650690›Full record

ArticleJournal of clinical monitoring and computing2025

Evaluating local ischemic preconditioning effects on skin perfusion using capillary refill time in healthy volunteers.

Elaine Cavalcante Dos Santos, Zoé Demailly, Jan Bakker, Fabio Silvio Taccone

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Article in Journal of clinical monitoring and computing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elaine Cavalcante Dos SantosDepartment of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium. elaine_meduece@yahoo.com.br.
Zoé DemaillyDepartment of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.
Jan BakkerDepartamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Avenida Diagonal Paraguay, Santiago, 8330077, Chile.
Fabio Silvio TacconeDepartment of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capillary refill time (CRT) is a vaso-occlusive test that allows the non-invasive assessment of skin perfusion. A vascular occlusive test (VOT) induces transient ischemia similar to that used in preconditioning ischemia. We hypothesized that CRT could be influenced by local tissue compression mimicking ischemic preconditioning when repeated measurements are performed. In healthy volunteers (n = 30), CRTs were performed twice on the index and middle fingers of the dominant hand and the index finger of the non-dominant hand at 15-minute intervals on the first day. On the second day, two CRT measurements were taken at 30-minute intervals. No significant differences were observed in CRT measurements repeated at 15- and 30-minute intervals. Additionally, baseline CRT values did not significantly differ between the fingers of the dominant and non-dominant hands on either study day. Repeated CRT measurements are not influenced by local ischemic preconditioning in the finger over short intervals.

Indexed as

CapillariesIschemic PreconditioningSkinAdultFemaleFingersHealthy VolunteersHumansIschemiaMaleMicrocirculationMiddle AgedRegional Blood FlowTime FactorsYoung AdultCapillary refill timeIschemic preconditioningMicrovascular reactivity

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.