Evidence map›Paper›PMID 40650681›Full record

ArticleApplied biochemistry and biotechnology2025

A Novel Peptide Derived from Casein Hydrolysates as a Growth Factor for Lactobacillus delbrueckii subsp. bulgaricus sp1.1.

Xinyue Hao, Xiaoning Song, Jing Ren, Olayemi Eyituoyo Dudu, Jingya Jiang, Jianhua Zeng, Song Wang, Huaxi Yi, Lanwei Zhang, Pimin Gong

Abstract read
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In one paragraph

Article in Applied biochemistry and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinyue HaoCollege of Food Science and Engineering, Ocean University of China, Qingdao, 266000, Shandong Province, China.
Xiaoning SongCollege of Food Science and Engineering, Ocean University of China, Qingdao, 266000, Shandong Province, China.
Jing RenCollege of Food Science and Engineering, Ocean University of China, Qingdao, 266000, Shandong Province, China.
Olayemi Eyituoyo DuduDepartment of Food Science and Technology, Bells University of Technology, Ota, Ogun State, Nigeria.
Jingya JiangCollege of Food Science and Engineering, Ocean University of China, Qingdao, 266000, Shandong Province, China.
Jianhua ZengCollege of Food Science and Engineering, Ocean University of China, Qingdao, 266000, Shandong Province, China.
Song WangQingdao Shangde Biotech Co., Ltd, Qingdao, 266,000, China.
Huaxi YiCollege of Food Science and Engineering, Ocean University of China, Qingdao, 266000, Shandong Province, China.
Lanwei ZhangCollege of Food Science and Engineering, Ocean University of China, Qingdao, 266000, Shandong Province, China.
Pimin GongCollege of Food Science and Engineering, Ocean University of China, Qingdao, 266000, Shandong Province, China. gongpimin@ouc.edu.cn.ORCID http://orcid.org/0000-0001-8581-2806

Funding

National Natural Science Foundation of China 32001664National Natural Science Foundation of China 32372289Taishan Industry Leading Talent of Shandong Province LJNY202101the Science and Technology Program of Xinjiang Production and ConstructionCorps 2024AB050
6 · The paper itself

Abstract

Milk proteins are traditionally recognized as nitrogen sources that support lactic acid bacteria (LAB) proliferation. Notably, oligopeptides may serve as the primary nitrogen source, and have the potential of enhancing the resistance of microbial strains to acidic environments. In this study, the impact of various casein hydrolysates on the proliferation of L. delbrueckii subsp. bulgaricus sp1.1 and the composition of peptides was studied. This study unveiled a novel peptide, KEGIHAQ, with a significant capacity to enhance both acid tolerance and proliferation of LAB. Inclusion of 0.1% (w/v) KEGIHAQ increased the number of viable bacteria by 1.68 times compared with the control and attained 1.34 × 10

Indexed as

CaseinsLactobacillus delbrueckiiPeptidescasein hydrolysateCaseinsPeptidesCasein hydrolysateHigh-density cultureLactic acid stressLactobacillus delbrueckii subsp. bulgaricusSDG 2

Identifiers

PMID40650681

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.