Evidence map›Paper›PMID 40650678›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

The value of serial [⁶⁸Ga]Ga-FAPI-04 PET/CT in predicting pathological response and evaluating therapeutic efficacy to neoadjuvant chemotherapy in breast cancer.

Shan Zheng, Fuqi Xu, Yun Chen, Zezhong Shao, Zenan Wu, Qun Liu, Ling Chen, Youzhi Zhu, Linying Chen, Dairong Cao and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Prospective comparison of [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  3. Comparison of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Diagnostic Performance ofNPJ breast cancer · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shan Zheng *Department of Nuclear Medicine, the First Affiliated Hospital, Fujian Medical University, No 20 Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, China.
Fuqi Xu *Department of Nuclear Medicine, the First Affiliated Hospital, Fujian Medical University, No 20 Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, China.
Yun Chen *Department of Nuclear Medicine, the First Affiliated Hospital, Fujian Medical University, No 20 Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, China.
Zezhong ShaoDepartment of Nuclear Medicine, the First Affiliated Hospital, Fujian Medical University, No 20 Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, China.
Zenan WuDepartment of Nuclear Medicine, the First Affiliated Hospital, Fujian Medical University, No 20 Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, China.
Qun LiuDepartment of Nuclear Medicine, Binhai Campus of the First Affiliated Hospital, National Regional Medical Center, Fujian Medical University, Changle District, Fuzhou, 350212, China.
Ling ChenDepartment of Thyroid and Breast Surgery, the First Affiliated Hospital, Fujian Medical University, No 20 Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, China.
Youzhi ZhuDepartment of Thyroid and Breast Surgery, the First Affiliated Hospital, Fujian Medical University, No 20 Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, China.
Linying ChenDepartment of Pathology, the First Affiliated Hospital, Fujian Medical University, No 20 Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, China.
Dairong CaoKey Laboratory of Radiation Biology of Fujian higher education institutions, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China. dairongcao@163.com.
Weibing MiaoDepartment of Nuclear Medicine, the First Affiliated Hospital, Fujian Medical University, No 20 Chazhong Road, Taijiang District, Fuzhou, 350005, Fujian Province, China. miaoweibing@126.com.

Funding

Fujian Provincial Clinical Key Specialty Construction Project No.2023SZDZK-HYXKJoint Funds for the Innovation of Science and Technology, Fujian Province No.2021Y9134National Natural Science Foundation of China (NSFC) No.82472012Natural Science Foundation of Fujian Province No.2022J01683Natural Science Foundation of Fujian Province No.2023J01584
6 · The paper itself

Abstract

objectiveTo investigate the clinical utility of serial [⁶⁸Ga]Ga-FAPI-04 PET/CT for predicting pathological response and evaluating therapeutic efficacy in breast cancer (BC) patients receiving neoadjuvant chemotherapy (NAC).

methodsA total of 64 biopsy-confirmed patients with BC were retrospectively included. Serial [

resultsSignificant reductions in [

conclusionThis study demonstrates that serial [

Indexed as

Breast NeoplasmsCoordination ComplexesNeoadjuvant TherapyPositron Emission Tomography Computed TomographyAdultAgedFemaleGallium RadioisotopesHumansMiddle AgedQuinolinesRetrospective StudiesTreatment Outcome68Ga-FAPICoordination ComplexesGallium RadioisotopesQuinolines[68Ga]Ga-FAPI-04Breast neoplasmNeoadjuvant chemotherapyPathological responsePET/CT

Identifiers

PMID40650678

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.