Evidence map›Paper›PMID 40650496›Full record

ArticleClinical trials (London, England)2025

Salvaging information from paused or stopped clinical studies.

Davey Smith, Thomas Fleming, Sara Gianella, Elizabeth Halloran, Sharon Hillier, Ira Longini, Laura Smeaton, Victor DeGruttola

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical trials (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Davey SmithUniversity of California San Diego, La Jolla, CA, USA.ORCID 0000-0003-3603-1733
Thomas FlemingUniversity of Washington, Seattle, WA, USA.ORCID 0000-0002-0420-5068
Sara GianellaUniversity of California San Diego, La Jolla, CA, USA.
Elizabeth HalloranFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Sharon HillierUniversity of Pittsburgh, Pittsburgh, PA, USA.
Ira LonginiUniversity of Florida, Gainesville, FL, USA.ORCID 0000-0002-2780-9382
Laura SmeatonHarvard University, Cambridge, MA, USA.ORCID 0000-0001-7243-4703
Victor DeGruttolaUniversity of California San Diego, La Jolla, CA, USA.

Funding

Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG); LOC 1/UM1AI068636 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, RAJESH T GANDHI · 2011 to 2026
$1073.1M
Statistical and Data Management Center (SDMC), AIDS Clinical Trials Group (ACTG)UM1AI068634 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Marlene Ann Cooper, Michael David Hughes · 2011 to 2026
$246.6M
SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026
$78.4M
NCATS NIH HHS UL1 TR001442NIAID NIH HHS P30 AI036214NIAID NIH HHS UM1 AI068617NIAID NIH HHS UM1 AI068634NIAID NIH HHS UM1 AI068636
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40650496
PMCPMC12331140

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.