Trial reportJournal of diabetes investigation2025
Relationship between medication use and non-attendance (missed appointment) from primary care visits among people with type 2 diabetes: The Japan Diabetes Outcome Intervention Trial-2 Large-Scale Trial 006 (J-DOIT2-LT006).
Trial report in Journal of diabetes investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
AIMS/
introductionTo clarify the relationship between medication use and primary care visit non-attendance (missed appointment) among people with type 2 diabetes. MATERIALS AND
methodsData of 2,200 patients registered in the Japan Diabetes Outcome Intervention Trial-2 Large-Scale trial were reviewed. The intervention group received multifaceted interventions encouraging regular visits. The hazard ratios (HR) and 95% confidence intervals (CI) of oral medications relative to not taking any oral medications were estimated using the Cox proportional hazards model, adjusted for district medical association ID, intervention, insulin usage, age, sex, and HbA1c. We also investigated whether the HRs differed based on the oral medication type. Furthermore, we divided the intervention and control groups into four groups based on medication use (taking/not taking oral medications and insulin therapy) and performed survival analysis for each group.
resultsThe HRs (95% CI) for oral medication use relative to not taking oral medications and for insulin use relative to not receiving insulin therapy were 0.178 (0.104-0.305) and 0.725 (0.378-1.352), respectively. Regardless of the type of oral medication, non-attendance was lower in the groups taking oral medications. The HRs (95% CI) in the groups taking only oral hypoglycemic agents, only other drugs, and both relative to no oral medication were 0.229 (0.126-0.417), 0.235 (0.112-0.494), and 0.148 (0.084-0.260), respectively. Only in the control group, non-attendance was more frequent with no medications than with oral medications, regardless of insulin (P < 0.01, respectively).
conclusionsOur findings suggest that taking oral medications might be important to prevent non-attendance among people with type 2 diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.