ArticleInternational endodontic journal2025
Activation of G protein-coupled parathyroid hormone receptors in rat incisor odontoblasts promotes mineralization via cyclic adenosine monophosphate, not Ca
Article in International endodontic journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Activation of G protein-coupled parathyroid hormone receptors in rat incisor odontoblasts promotes mineralization via cyclic adenosine monophosphate, not CaInternational endodontic journal · 2025Article
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5 authors.
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Abstract
aimParathyroid hormone (PTH) and its Gα METHODOLOGY: We obtained acutely isolated odontoblasts from newborn Wistar rats and analysed the mineralization ability by Alizarin red staining. Intracellular-free Ca
resultsGranulated PTH was detected in the vascular area of the dental pulp periphery. Application of the non-selective PTH receptor agonist DPC AJ1951 increased cAMP levels in odontoblasts. This increase was significantly inhibited by the non-selective PTH receptor antagonist 4185-v and the adenylyl cyclase inhibitor SQ 22536. However, applying the non-selective PTH receptor agonist DPC AJ1951 did not increase the intracellular Ca
conclusionThus, the present study suggests that PTH from the bloodstream functionally activates the Gα
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