Evidence map›Paper›PMID 40650316›Full record

ArticleInternational journal of molecular sciences2025

The Role of Single Nucleotide Polymorphisms at the Arg399Gln Locus of the

Beata Smolarz, Bartosz Cieślik-Wolski, Józef Kozak, Honorata Łukasiewicz, Dariusz Samulak, Dariusz Trzmielak, Hanna Romanowicz, Marianna Makowska

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Beata SmolarzLaboratory of Cancer Genetics, Department of Pathology, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.ORCID 0000-0003-3168-062X
Bartosz Cieślik-WolskiDepartment of Thoracic Surgery, Medical University of Lodz, Memorial Copernicus Hospital, 93-338 Lodz, Poland.
Józef KozakDepartment of Thoracic Surgery, Medical University of Lodz, Memorial Copernicus Hospital, 93-338 Lodz, Poland.
Honorata ŁukasiewiczDepartment of Nursing, Faculty of Medicine and Health Sciences, The President Stanisław Wojciechowski Calisia University, 62-800 Kalisz, Poland.
Dariusz SamulakDepartment of Obstetrics and Gynecology and Gynecological Oncology, Regional Hospital in Kalisz, 62-800 Kalisz, Poland.
Dariusz TrzmielakDepartment of Science, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.
Hanna RomanowiczLaboratory of Cancer Genetics, Department of Pathology, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.
Marianna MakowskaDepartment of Anesthesiology and Operative Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, 10117 Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, an increasingly important role in the etiopathogenesis of lung cancer has been attributed to genetic predisposition. Current genetic research suggests that the increased risk of this cancer may be due to gene polymorphism within repair genes. In the case of lung cancer, observations about genes involved in the DNA repair system by cutting bases of nitrogen-base excision repair (BER)-seem to be interesting. Most attention has been devoted to the

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsPolymorphism, Single NucleotideX-ray Repair Cross Complementing Protein 1AdultAgedCase-Control StudiesFemaleGenetic Predisposition to DiseaseGenotypeHumansMaleMiddle AgedRisk FactorsX-ray Repair Cross Complementing Protein 1XRCC1 protein, humannon-small cell lung cancerpolymorphismXRCC1

Identifiers

PMID40650316
PMCPMC12249988

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.