Evidence map›Paper›PMID 40650311›Full record

ArticleInternational journal of molecular sciences2025

Molecular Hybrids of Thiazolidinone: Bridging Redox Modulation and Cancer Therapy.

Nourah A Al Zahrani, Manal A Alshabibi, Abrar A Bakr, Fahad A Almughem, Abdullah A Alshehri, Huda A Al-Ghamdi, Essam A Tawfik, Laila A Damiati

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nourah A Al ZahraniDepartment of Chemistry, College of Science, University of Jeddah, Jeddah 23218, Saudi Arabia.
Manal A AlshabibiAdvanced Diagnostics and Therapeutics Institute, Health Sector, King Abdulaziz City for Science and Technology (KACST), Riyadh 11442, Saudi Arabia.
Abrar A BakrAdvanced Diagnostics and Therapeutics Institute, Health Sector, King Abdulaziz City for Science and Technology (KACST), Riyadh 11442, Saudi Arabia.
Fahad A AlmughemAdvanced Diagnostics and Therapeutics Institute, Health Sector, King Abdulaziz City for Science and Technology (KACST), Riyadh 11442, Saudi Arabia.ORCID 0000-0001-9614-7557
Abdullah A AlshehriAdvanced Diagnostics and Therapeutics Institute, Health Sector, King Abdulaziz City for Science and Technology (KACST), Riyadh 11442, Saudi Arabia.ORCID 0000-0003-0358-4155
Huda A Al-GhamdiDepartment of Chemistry, College of Science, University of Jeddah, Jeddah 23218, Saudi Arabia.ORCID 0000-0001-9475-0598
Essam A TawfikAdvanced Diagnostics and Therapeutics Institute, Health Sector, King Abdulaziz City for Science and Technology (KACST), Riyadh 11442, Saudi Arabia.
Laila A DamiatiDepartment of Biological Science, College of Science, University of Jeddah, Jeddah 23218, Saudi Arabia.ORCID 0000-0002-4746-0915

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterocyclic compounds have shown that they hold significant therapeutic activities, highlighting the importance of discovering and developing novel candidates against cancers, infections, and oxidative stress-associated disorders. In this study, we demonstrated the biological activity of our previously synthesized thiazolidinone derivatives (TZDs-1, 6, and 7). Furthermore, we synthesized and structurally characterized a new derivative (TZD-5) using IR,

Indexed as

Antineoplastic AgentsAntioxidantsNeoplasmsThiazolidinesA549 CellsCell Line, TumorCell SurvivalHep G2 CellsHumansOxidation-ReductionAntineoplastic AgentsAntioxidantsThiazolidinesantioxidant propertiesbiological activitychemical synthesiselectron-donating groupsthiazolidinone derivatives

Identifiers

PMID40650311
PMCPMC12249957

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.