Evidence map›Paper›PMID 40650194›Full record

ArticleInternational journal of molecular sciences2025

Predicting the Metastatic Potential of Papillary Thyroid Microcarcinoma Based on the Molecular Profile of Preoperative Cytology Specimens.

Sergei A Lukyanov, Sergei E Titov, Aria V Dzodzaeva, Vladimir E Vanushko, Dmitry G Beltsevich, Yuliya A Veryaskina, Semyon V Kupriyanov, Ekaterina V Bondarenko, Ekaterina A Troshina, Liliya S Urusova and 1 more

Abstract read
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Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sergei A LukyanovDepartment of General Surgery, South Ural State Medical University, 454141 Chelyabinsk, Russia.ORCID 0000-0001-5559-9872
Sergei E TitovDepartment of the Structure and Function of Chromosomes, Institute of Molecular and Cellular Biology, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0001-9401-5737
Aria V DzodzaevaNational Medical Research Center for Endocrinology, 115478 Moscow, Russia.
Vladimir E VanushkoNational Medical Research Center for Endocrinology, 115478 Moscow, Russia.
Dmitry G BeltsevichNational Medical Research Center for Endocrinology, 115478 Moscow, Russia.
Yuliya A VeryaskinaDepartment of the Structure and Function of Chromosomes, Institute of Molecular and Cellular Biology, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-3799-9407
Semyon V KupriyanovLaboratory of Evolutionary Cytogenetics, National Research Tomsk State University, 634050 Tomsk, Russia.
Ekaterina V BondarenkoNational Medical Research Center for Endocrinology, 115478 Moscow, Russia.ORCID 0000-0003-2122-2297
Ekaterina A TroshinaNational Medical Research Center for Endocrinology, 115478 Moscow, Russia.
Liliya S UrusovaNational Medical Research Center for Endocrinology, 115478 Moscow, Russia.ORCID 0000-0001-6891-0009
Sergei V SergiykoDepartment of General Surgery, South Ural State Medical University, 454141 Chelyabinsk, Russia.

Funding

The study was supported by the Russian Science Foundation project No. 20-14-00074-PThe study was supported by the Tomsk State University Development Program Priority-2030This research was funded by the Ministry of Science and Higher Education of the Russian Federation Grant Number: 075-15-2022-310
6 · The paper itself

Abstract

The strategy of active surveillance for papillary thyroid microcarcinoma (PTMC) is becoming increasingly popular within the global medical community. A key criterion for selecting this strategy is the absence of any signs of lymphogenic or distant metastases. The present study assessed the diagnostic accuracy of molecular genetic markers for predicting the metastatic potential of patients with PTMC. We evaluated the expression levels of 33 molecular genetic markers in cytology samples from 92 patients with PTMC and confirmed histological diagnosis. Among these patients, 32 had metastases to regional cervical lymph nodes. Our findings revealed the upregulated expression of the

Indexed as

Biomarkers, TumorCarcinoma, PapillaryThyroid NeoplasmsAdultAgedFemaleGene Expression Regulation, NeoplasticHumansLymphatic MetastasisMaleMicroRNAsMiddle AgedNeoplasm MetastasisBiomarkers, TumorMicroRNAsFN1HMGA2metastaticmiRNA-146bmiRNA-148bmiRNA-7molecular testingpapillary thyroid microcarcinomaSLC26A7TIMP1

Identifiers

PMID40650194
PMCPMC12249573

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.