Evidence map›Paper›PMID 40650186›Full record

ArticleInternational journal of molecular sciences2025

Assessment of Abuse Potential of Three Indazole-Carboxamide Synthetic Cannabinoids 5F-ADB, MDMB-4en-PINACA and ADB-4en-PINACA.

Yanling Qiao, Xuesong Shi, Kaixi Li, Lixin Kuai, Xiangyu Li, Bin Di, Peng Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yanling QiaoSchool of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Xuesong ShiSchool of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Kaixi LiSchool of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Lixin KuaiSchool of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Xiangyu LiOffice of China National Narcotics Control Commission, China Pharmaceutical University Joint Laboratory on Key Technologies of Narcotics Control, Beijing 100193, China.
Bin DiSchool of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Peng XuOffice of China National Narcotics Control Commission, China Pharmaceutical University Joint Laboratory on Key Technologies of Narcotics Control, Beijing 100193, China.

Funding

National Key Research and Development Program No. 2022YFC3300905
6 · The paper itself

Abstract

5F-ADB, MDMB-4en-PINACA and ADB-4en-PINACA are three potent indazole-carboxamide synthetic cannabinoids (SCs) that have been widely abused in recent years. However, the pharmacological research on these compounds remains limited, especially in vivo research data. The purpose of the present study was to investigate the pharmacological effects of 5F-ADB, MDMB-4en-PINACA and ADB-4en-PINACA in mice, comparing their in vivo effects with those caused by Δ

Indexed as

CannabinoidsIndazolesSubstance-Related DisordersAnimalsLocomotionMaleMice5F-ADB cannabinoidCannabinoidsIndazolesabuse potentialconditioned place preferenceprecipitated withdrawalsynthetic cannabinoidstetrad effects

Identifiers

PMID40650186
PMCPMC12249697

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.