Evidence map›Paper›PMID 40650169›Full record

SynthesisInternational journal of molecular sciences2025

Molecular Guardians of Oocyte Maturation: A Systematic Review on TUBB8, KIF11, and CKAP5 in IVF Outcomes.

Charalampos Voros, Ioakeim Sapantzoglou, Diamantis Athanasiou, Antonia Varthaliti, Despoina Mavrogianni, Kyriakos Bananis, Antonia Athanasiou, Aikaterini Athanasiou, Georgios Papadimas, Athanasios Gkirgkinoudis and 11 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Charalampos VorosDepartment of Obstetrics and Gynecology, 'Alexandra' General Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0001-9477-7619
Ioakeim SapantzoglouDepartment of Obstetrics and Gynecology, 'Alexandra' General Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Diamantis AthanasiouIVF Athens Reproduction Center V. Athanasiou, 15123 Maroussi, Greece.
Antonia VarthalitiDepartment of Obstetrics and Gynecology, 'Alexandra' General Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0009-0008-8725-7103
Despoina MavrogianniDepartment of Obstetrics and Gynecology, 'Alexandra' General Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0003-1220-6594
Kyriakos BananisKing's College Hospitals NHS Foundation Trust, London SE5 9RS, UK.
Antonia AthanasiouIVF Athens Reproduction Center V. Athanasiou, 15123 Maroussi, Greece.
Aikaterini AthanasiouIVF Athens Reproduction Center V. Athanasiou, 15123 Maroussi, Greece.
Georgios PapadimasAthens Medical School, National and Kapodistrian University of Athens, 15772 Athens, Greece.
Athanasios GkirgkinoudisDepartment of Obstetrics and Gynecology, 'Alexandra' General Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0003-1376-7895
Ioannis PapapanagiotouAthens Medical School, National and Kapodistrian University of Athens, 15772 Athens, Greece.ORCID 0000-0002-9723-5054
Kyriaki MigklisAthens Medical School, National and Kapodistrian University of Athens, 15772 Athens, Greece.
Dimitrios VaitsisAthens Medical School, National and Kapodistrian University of Athens, 15772 Athens, Greece.
Aristotelis-Marios KoulakmanidisDepartment of Obstetrics and Gynecology, 'Alexandra' General Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Dimitris Mazis KourakosAthens Medical School, National and Kapodistrian University of Athens, 15772 Athens, Greece.
Sofia IvanidouAthens Medical School, National and Kapodistrian University of Athens, 15772 Athens, Greece.
Maria Anastasia DaskalakiDepartment of Obstetrics and Gynecology, 'Alexandra' General Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Marianna TheodoraDepartment of Obstetrics and Gynecology, 'Alexandra' General Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0001-8280-7796
Panagiotis AntsaklisDepartment of Obstetrics and Gynecology, 'Alexandra' General Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0003-2106-5922
Dimitrios LoutradisAthens Medical School, National and Kapodistrian University of Athens, 15772 Athens, Greece.ORCID 0000-0002-8686-594X
Georgios DaskalakisDepartment of Obstetrics and Gynecology, 'Alexandra' General Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0001-7108-211X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficacy of in vitro fertilization (IVF) is significantly hindered by early embryonic developmental failure and oocyte maturation arrest. Recent findings in reproductive genetics have identified several oocyte-specific genes-

Indexed as

Cytoskeletal ProteinsFertilization in VitroKinesinsOocytesTubulinFemaleHumansMutationCytoskeletal ProteinsKIF11 protein, humanKinesinsTUBB8 protein, humanTubulinassisted reproductive technologyCKAP5cytoskeletonearly embryonic arrestfemale infertilitygenetic variantsIVF failureKIF11meiotic spindlemicrotubule dynamicsoocyte maturation arrestspindle assemblyTUBB8

Identifiers

PMID40650169
PMCPMC12250275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.