ArticleInternational journal of molecular sciences2025
Molecular Determinants of TMC Protein Biogenesis and Trafficking.
Dedong Shao, Jinru Tan, Xiaozhi Fan, Yilai Shu, Qianhui Qu, Yi-Quan Tang
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
6 authors.
Dedong ShaoState Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, ENT Institute and Otorhinolaryngology Department of Eye & ENT Hospital, Fudan University, Shanghai 200032, China.
Jinru TanState Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, ENT Institute and Otorhinolaryngology Department of Eye & ENT Hospital, Fudan University, Shanghai 200032, China.
Xiaozhi FanState Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, ENT Institute and Otorhinolaryngology Department of Eye & ENT Hospital, Fudan University, Shanghai 200032, China.ORCID 0009-0008-7246-0205 Yilai ShuState Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, ENT Institute and Otorhinolaryngology Department of Eye & ENT Hospital, Fudan University, Shanghai 200032, China.
Qianhui QuShanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai 200031, China.
Yi-Quan TangState Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, ENT Institute and Otorhinolaryngology Department of Eye & ENT Hospital, Fudan University, Shanghai 200032, China.ORCID 0000-0002-6639-8897 Funding
Ministry of Science and Technology of the People's Republic of China 2021ZD0203303National Natural Science Foundation of China 32170694Shanghai Municipal Science and Technology Major Project 2018SHZDZX01The National Key R&D Program of China 2024YFC2511100/2024YFC2511104
6 · The paper itselfAbstract
Transmembrane channel-like (TMC) proteins are essential for hearing and balance; however, the molecular mechanisms that regulate their proper folding and membrane targeting remain poorly understood. Here, we establish
Indexed as
Caenorhabditis elegans ProteinsIon ChannelsAnimalsAnimals, Genetically ModifiedCaenorhabditis elegansCell LineDisulfidesHumansMembrane ProteinsMuscle CellsMutationNeuronsProtein TransportCaenorhabditis elegans ProteinsDisulfidesIon ChannelsMembrane ProteinsTMC-1 protein, C elegansTMC1 protein, humantmc-2 protein, C elegansAlphaFolddeafnessTMCtrafficking
Identifiers
PMID40650136
PMCPMC12250529
What OpenQuestion holds
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LicenceCC BY
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