Evidence map›Paper›PMID 40650091›Full record

ArticleInternational journal of molecular sciences2025

Triazole-imidazo[1,2-

Chiara Brullo, Barbara Marengo, Cinzia Domenicotti, Matteo Lusardi, Elena Cichero, Annalisa Salis, Debora Caviglia, Eleonora Russo, Andrea Spallarossa

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chiara BrulloDepartment of Pharmacy, University of Genoa, Viale Benedetto XV 3, 16132 Genova, Italy.ORCID 0000-0002-2575-7726
Barbara MarengoDepartment of Experimental Medicine (DIMES), University of Genova, Via Leon Battista Alberti 2, 16132 Genoa, Italy.ORCID 0000-0003-3056-6569
Cinzia DomenicottiDepartment of Experimental Medicine (DIMES), University of Genova, Via Leon Battista Alberti 2, 16132 Genoa, Italy.ORCID 0000-0002-5003-7333
Matteo LusardiDepartment of Pharmacy, University of Genoa, Viale Benedetto XV 3, 16132 Genova, Italy.ORCID 0000-0002-7003-7891
Elena CicheroDepartment of Pharmacy, University of Genoa, Viale Benedetto XV 3, 16132 Genova, Italy.
Annalisa SalisDepartment of Experimental Medicines, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.ORCID 0000-0002-3082-2908
Debora CavigliaDepartment of Pharmacy, University of Genoa, Viale Benedetto XV 3, 16132 Genova, Italy.
Eleonora RussoDepartment of Pharmacy, University of Genoa, Viale Benedetto XV 3, 16132 Genova, Italy.ORCID 0000-0002-5856-7929
Andrea SpallarossaDepartment of Pharmacy, University of Genoa, Viale Benedetto XV 3, 16132 Genova, Italy.ORCID 0000-0002-3360-7146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To further extend the structure-activity relationships on previously identified anti-proliferative imidazo-pyrazoles, a novel series of compounds was designed and synthesized. In the obtained derivatives (

Indexed as

Antineoplastic AgentsImidazolesKeratinocytesMelanomaPyrazolesTriazolesCell Line, TumorCell ProliferationCell SurvivalHumansStructure-Activity RelationshipAntineoplastic AgentsImidazolesPyrazolesTriazolesanti-proliferative agentscritical micelle concentrationdrug deliveryimidazo-pyrazole derivativesmelanoma cellssurfactants

Identifiers

PMID40650091
PMCPMC12249857

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.